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急性结肠憩室炎治疗的现状:系统评价。

Current status of the treatment of acute colonic diverticulitis: a systematic review.

机构信息

Department of General and Digestive Surgery, Bellvitge University Hospital, University of Barcelona, IDIBELL (Bellvitge Biomedical Research Institute), Barcelona, Spain.

出版信息

Colorectal Dis. 2012 Jan;14(1):e1-e11. doi: 10.1111/j.1463-1318.2011.02766.x.

Abstract

AIM

This paper addresses the current status of the treatment of acute colonic diverticulitis by an evidence-based review.

METHOD

A systematic search in PUBMED, MEDLINE, EMBASE and Google scholar on colonic diverticulitis was performed. Diagnostic tools, randomized controlled trials, non-randomized comparative studies, observational epidemiological studies, national and international guidelines, reviews of observational studies on elective and emergency surgical treatment of diverticulitis, and studies of prognostic significance were reviewed. Criteria for eligibility of the studies were diagnosis and classification, medical treatment, inpatients and outpatients, diverticulitis in young patients, immunosuppression, recurrence, elective resection, emergency surgery, and predictive factors.

RESULTS

Some 92 publications were selected for comprehensive review. The review highlighted that computed tomography is the most effective test in the diagnosis and staging of acute diverticulitis; outpatient treatment can be performed for uncomplicated diverticulitis in patients without associated comorbidities; conservative treatment is aimed at those patients with uncomplicated acute diverticulitis; elective surgery must be done on an individual basis; laparoscopic approach for elective treatment of diverticulitis is appropriate but may be technically complex; in perforated diverticulitis, resection with primary anastomosis is a safe procedure that requires experience and should take into account strict exclusion criteria.

CONCLUSION

The heterogeneity of patients with colonic diverticular disease means that both elective and urgent treatment should be tailored on an individual basis.

摘要

目的

本文通过循证综述探讨急性结肠憩室炎的治疗现状。

方法

在 PUBMED、MEDLINE、EMBASE 和 Google scholar 上对结肠憩室炎进行了系统检索。对诊断工具、随机对照试验、非随机对照研究、观察性流行病学研究、国家和国际指南、择期和急诊手术治疗憩室炎的观察性研究综述以及预后意义的研究进行了综述。研究入选标准为诊断和分类、内科治疗、住院和门诊、年轻患者的憩室炎、免疫抑制、复发、择期切除、急诊手术和预测因素。

结果

选择了 92 篇论文进行综合评价。综述强调,计算机断层扫描是诊断和分期急性憩室炎最有效的检查方法;对于无相关合并症的单纯性憩室炎患者,可以进行门诊治疗;保守治疗针对的是单纯性急性憩室炎患者;择期手术必须个体化进行;腹腔镜治疗憩室炎是一种合适的方法,但可能具有技术复杂性;对于穿孔性憩室炎,切除加一期吻合是一种安全的手术,但需要经验,并应考虑严格的排除标准。

结论

结肠憩室疾病患者的异质性意味着择期和紧急治疗都应根据个体情况进行调整。

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