Institute for Infectious and Tropical Diseases, University of Brescia, Brescia, Italy.
Clin Microbiol Infect. 2012 May;18(5):468-74. doi: 10.1111/j.1469-0691.2011.03596.x. Epub 2011 Aug 16.
The aim of this study was to investigate travel-associated morbidity in European travellers in 2009 in comparison with 2008, with a particular emphasis on emerging infectious diseases with the potential for introduction into Europe. Diagnoses with demographic, clinical and travel-related predictors of disease from ill returning travelers presenting to 12 core EuroTravNet sites from January to December 2009 were analysed. A total of 6392 patients were seen at EuroTravNet core sites in 2009, as compared with 6957 in 2008. As compared with 2008, there was a marked increase in the number of travellers exposed in North America and western Europe. Respiratory illnesses, in particular pandemic A(H1N1) influenza, influenza-like syndromes, and tuberculosis, were also observed more frequently. A significant increase in reported dengue cases in 2009 as compared with 2008 was observed (n = 172, 2.7% vs. n = 131, 1.90%) (p 0.002). The numbers of malaria and chikungunya cases were also increasing, although not significantly. Two deaths were recorded: visceral leishmaniasis and sepsis in a Sudanese migrant, and Acinetobacter sp. pneumonia in a patient who had visited Spain. This is the most comprehensive study of travel-related illness in Europe in 2009 as compared with 2008. A significant increase in travel-related respiratory and vector-borne infections was observed, highlighting the potential risk for introduction of these diseases into Europe, where competent vectors are present. The number of traveller deaths is probably underestimated. The possible role of the travellers in the emergence of infectious diseases of public health concern is highlighted.
本研究旨在调查 2009 年与 2008 年相比，欧洲旅行者的旅行相关发病率，特别关注具有传入欧洲潜力的新发传染病。对 2009 年 1 月至 12 月期间，12 个核心 EuroTravNet 站点就诊的患有疾病的返回旅行者进行了人口统计学、临床和旅行相关预测因素分析。与 2008 年相比，2009 年在 EuroTravNet 核心站点就诊的患者共 6392 例，而 2008 年为 6957 例。与 2008 年相比，暴露于北美和西欧的旅行者人数明显增加。呼吸道疾病，特别是大流行性 A(H1N1)流感、流感样综合征和结核病的发病率也更高。与 2008 年相比，2009 年报告的登革热病例数显著增加（n=172，2.7%比 n=131，1.90%）（p<0.002）。疟疾病例和基孔肯雅热病例也在增加，尽管没有显著增加。记录了两例死亡：一名苏丹移民的内脏利什曼病和败血症，以及一名曾前往西班牙的患者的不动杆菌肺炎。这是 2009 年与 2008 年相比，对欧洲旅行相关疾病最全面的研究。观察到与旅行相关的呼吸道和虫媒传染病显著增加，突显了这些疾病传入存在媒介的欧洲的潜在风险。旅行者死亡人数可能被低估。旅行者在新发传染病出现中的可能作用突显了公共卫生关注。
