直接荧光抗体检测结合培养用于诊断 2009 年 H1N1 流感 A 型。
Direct fluorescent-antibody testing followed by culture for diagnosis of 2009 H1N1 influenza A.
机构信息
Phoenix Children's Hospital, Pediatric Intensive Care Unit, Phoenix, Arizona 85016, USA.
出版信息
J Clin Microbiol. 2011 Oct;49(10):3673-4. doi: 10.1128/JCM.05255-11. Epub 2011 Aug 17.
Abstract
During the 2009 H1N1 influenza A outbreak, 773 children were tested for influenza by direct fluorescent-antibody testing with PCR confirmation. Direct fluorescent-antibody testing has a specificity of 99.6% but a sensitivity of only 65.0%. Physicians should recognize diagnostic limitations of direct fluorescent-antibody testing, which missed one-third of infected individuals.
摘要
在 2009 年甲型 H1N1 流感爆发期间，773 名儿童通过直接荧光抗体检测与 PCR 确认进行了流感检测。直接荧光抗体检测的特异性为 99.6%，但敏感性仅为 65.0%。医生应该认识到直接荧光抗体检测的诊断局限性，这种检测方法漏诊了三分之一的感染者。
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