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快速免疫层析抗原检测在诊断 2009 年甲型 H1N1 流感病毒感染中的作用。

Role of rapid immunochromatographic antigen testing in diagnosis of influenza A virus 2009 H1N1 infection.

机构信息

Department of Pathology , University of Texas Southwestern Medical Center and Medical Microbiology Consulting, LLC, Dallas, Texas 75235, USA.

出版信息

J Clin Microbiol. 2010 Jan;48(1):22-5. doi: 10.1128/JCM.02268-09. Epub 2009 Dec 9.

DOI:10.1128/JCM.02268-09
PMID:20007399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2812308/
Abstract

Rapid antigen testing using immunochromatographic devices has become a diagnostic mainstay for detection of influenza virus and respiratory syncytial virus, the two major viruses infecting the respiratory tract. Recent studies have indicated that poor performance in the detection of the novel influenza A virus 2009 H1N1 should preclude their use. A survey of influenza diagnostic methods available on ClinMicroNet and Division C, the two ASM list servers, revealed that, despite this reported poor performance, a majority of the laboratories surveyed intend to continue to offer this testing during the current influenza season. Our two experts have been asked to consider the following question: what is the role of rapid immunochromatographic antigen testing in the laboratory diagnosis of influenza A virus infection during the current 2009 H1N1 pandemic?

摘要

使用免疫层析设备的快速抗原检测已成为检测流感病毒和呼吸道合胞病毒(感染呼吸道的两种主要病毒)的主要诊断方法。最近的研究表明,这种方法在检测新型甲型 H1N1 流感病毒方面表现不佳,因此不应使用。对 ClinMicroNet 和 ASM 列表服务器的 Division C 上可用的流感诊断方法进行的调查显示,尽管报告称该方法性能不佳,但大多数接受调查的实验室仍计划在当前流感季节继续提供此项检测。我们的两位专家被要求考虑以下问题:在当前 2009 年 H1N1 大流行期间,快速免疫层析抗原检测在甲型流感病毒感染的实验室诊断中的作用是什么?

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本文引用的文献

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Rapid antigen tests for diagnosis of pandemic (Swine) influenza A/H1N1.用于诊断甲型H1N1大流行性(猪)流感的快速抗原检测
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Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing.通过直接荧光抗原检测排除新型甲型H1N1流感病毒感染。
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