Veterinary Clinical Studies, UCD Veterinary Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland.
Ir Vet J. 2010 Jun 1;63(6):373-9. doi: 10.1186/2046-0481-63-6-373.
The objective of this study was to examine the impact of hospitalisation and antimicrobial drug administration on the prevalence of resistance in commensal faecal E. coli of horses. Faecal samples were collected from ten hospitalised horses treated with antimicrobials, ten hospitalised horses not treated with antimicrobials and nine non-hospitalised horses over a consecutive five day period and susceptibility testing was performed on isolated E. coli. Results revealed that hospitalisation alone was associated with increased prevalence of antimicrobial resistance and multidrug resistance in commensal E. coli of horses. Due to the risk of transfer of resistance between commensal and pathogenic bacteria, veterinarians need to be aware of possible resistance in commensal bacteria when treating hospitalised horses.
本研究旨在探讨住院和抗菌药物治疗对马肠道共生大肠杆菌耐药性流行的影响。连续五天采集了 10 头接受抗菌药物治疗的住院马、10 头未接受抗菌药物治疗的住院马和 9 头非住院马的粪便样本,并对分离出的大肠杆菌进行了药敏试验。结果表明,仅住院就与马肠道共生大肠杆菌的抗菌药物耐药性和多药耐药性增加有关。由于共生菌和病原菌之间耐药性转移的风险,兽医在治疗住院马时需要注意共生菌可能存在的耐药性。