Analytic Cytology Laboratory, Shantou University Medical College, No. 22 Xinling Road, Shantou 515041, Guangdong, PR China.
Ecotoxicol Environ Saf. 2011 Nov;74(8):2141-7. doi: 10.1016/j.ecoenv.2011.07.038. Epub 2011 Aug 17.
Primitive electronic-waste recycling resulted in serious pollution of polychlorinated biphenyls (PCBs) in the environment of Guiyu, China. We aimed to assess body burdens of PCBs and potential health risks for neonates. Umbilical cord blood (UCB) samples were collected from Guiyu, and the control area of Chaonan, China. PCBs in UCB were determined by gas chromatography coupled with mass spectrometry. The median ∑PCBs concentration was 338.56 ng g⁻¹ lipid in UCB samples from Guiyu, vs. 140.16 ng g⁻¹ lipid in samples from Chaonan. Mothers' involvement in electronic-waste recycling activities and house used as family workshop were the significant factors that contributed to ∑PCBs level. Some individual PCB congeners were found to correlate with reduced neonatal height, weight, Apgar scores, gestational age, and body mass index (BMI). Difference of ∑PCBs level was found between normal birth and adverse birth outcomes. Neonates from Guiyu are exposed to high levels of PCBs; prenatal exposure to PCBs appears to influence neonatal health, but still needs further confirmation.
原始的电子垃圾回收导致中国贵屿地区多氯联苯（PCBs）严重污染。我们旨在评估 PCBs 的体内负荷和对新生儿的潜在健康风险。采集了来自贵屿和中国潮南对照区的脐带血（UCB）样本。采用气相色谱-质谱联用技术测定 UCB 中的 PCBs。贵屿 UCB 中∑PCBs 的中位数浓度为 338.56ng g⁻¹脂质，而潮南样本中的浓度为 140.16ng g⁻¹脂质。母亲参与电子垃圾回收活动和家庭作坊是导致∑PCBs 水平升高的重要因素。一些特定的 PCB 同系物与新生儿身高、体重、阿普加评分、胎龄和体重指数（BMI）降低有关。正常分娩和不良分娩结局之间存在∑PCBs 水平的差异。贵屿的新生儿暴露于高水平的 PCBs 中；产前暴露于 PCBs 似乎会影响新生儿健康，但仍需要进一步证实。
