Clinical experience with ciprofloxacin: analysis of a multicenter study.

In a multicenter study of 132 patients treated with ciprofloxacin for a variety of infections, 35 were microbiologically proven. Of these, bacteriologic cure equaled 85.7%, while improvement equaled 11.4%; failure was 2.9%. Clinical cure equaled 65.8%, while improvement was 26.3%. Failure was reported for 7.9% of cases. A total of 46 (35.9%) infections were classified as chronic. Overall, six of the 132 patients had adverse reactions. Two were related definitely to ciprofloxacin therapy. Therapy with ciprofloxacin was discontinued in two (1.5%) patients because of adverse effects.