Chevis S A, Oakes W T
J Miss State Med Assoc. 1989 May;30(5):145-8.
The authors report a multicenter study of 19 patients treated with ciprofloxacin (mean daily dosage, 972 mg per day; mean duration of treatment, 8.5 days) for a variety of infections, ten microbiologically proven. Of these, bacteriologic cure equaled 70%, and improvement 30%. Overall, clinical cure equaled 73.7%, while improvement was 15.8%. No infections were classified as chronic. One adverse reaction was noted; a case of severe vomiting classified as related definitely to ciprofloxacin therapy. The patient discontinued therapy.
作者报告了一项多中心研究,19例患者因各种感染接受环丙沙星治疗(平均每日剂量为972毫克/天;平均治疗持续时间为8.5天),其中10例经微生物学证实。在这些患者中,细菌学治愈率为70%,改善率为30%。总体而言,临床治愈率为73.7%,改善率为15.8%。没有感染被归类为慢性感染。记录到1例不良反应;1例严重呕吐被明确归类为与环丙沙星治疗有关。该患者停止了治疗。