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库欣综合征伴低血清皮质醇水平：吸入性类固醇的作用。

Cushing's syndrome with low levels of serum cortisol: the role of inhaled steroids.

机构信息

Department of Endocrinology, Barts and the London School of Medicine.

出版信息

Clin Med (Lond). 2011 Aug;11(4):404-5. doi: 10.7861/clinmedicine.11-4-404.

DOI:10.7861/clinmedicine.11-4-404
PMID:21853845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5873758/
Abstract

With the introduction of new drugs and new devices believed to have less potential for systemic effects, the propensity for potent inhaled glucocorticoids to cause potent hypothalamic—pituitary—adrenal axis suppression is still under recognised.

摘要

随着新药物和新器械的引入，这些药物和器械被认为对全身影响的潜力较小，但仍未充分认识到强效吸入性糖皮质激素引起强效下丘脑-垂体-肾上腺轴抑制的倾向。

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本文引用的文献

1
Clinical Review#: The diagnosis and management of central hypoadrenalism.临床综述：中枢性肾上腺功能减退症的诊断与治疗。
J Clin Endocrinol Metab. 2010 Nov;95(11):4855-63. doi: 10.1210/jc.2010-0982. Epub 2010 Aug 18.
2
The properties of inhaled corticosteroids: similarities and differences.吸入性糖皮质激素的特性：异同
Prim Care Respir J. 2007 Jun;16(3):149-54. doi: 10.3132/pcrj.2007.00038.
3
Pharmacologic characteristics and adrenal suppression with newer inhaled corticosteroids: A comparison of ciclesonide and fluticasone propionate.新型吸入性糖皮质激素的药理特性及肾上腺抑制作用：环索奈德与丙酸氟替卡松的比较
Clin Ther. 2006 Mar;28(3):319-31. doi: 10.1016/j.clinthera.2006.03.003.
4
Adrenal suppression with dry powder formulations of fluticasone propionate and mometasone furoate.丙酸氟替卡松和糠酸莫米松干粉制剂导致的肾上腺抑制
Am J Respir Crit Care Med. 2004 Nov 1;170(9):960-6. doi: 10.1164/rccm.200404-500OC. Epub 2004 Jun 7.
5
Adrenal function as assessed by low-dose adrenocorticotropin hormone test before and after switching from inhaled beclomethasone dipropionate to inhaled fluticasone propionate.在从吸入丙酸倍氯米松转换为吸入丙酸氟替卡松前后，通过低剂量促肾上腺皮质激素试验评估肾上腺功能。
J Asthma. 2003;40(5):515-22. doi: 10.1081/jas-120018781.