Max F. Perutz Laboratories, University of Vienna, Dr. Bohr-Gasse 1, 1030 Vienna, Austria.
Curr Biol. 2011 Aug 23;21(16):R634-6. doi: 10.1016/j.cub.2011.06.059.
To segregate chromosomes properly, the cell must prevent merotely, an error that occurs when a single kinetochore is attached to microtubules emanating from both spindle poles. Recent evidence suggests that cooperation between Pcs1/Mde4 and condensin complexes plays an important role in preventing merotely.
为了正确分离染色体，细胞必须防止极体发生错误，极体是指一个动粒连接来自两个纺锤极的微管的错误。最近的证据表明，Pcs1/Mde4 和凝聚素复合物之间的合作在防止极体发生错误方面发挥着重要作用。
