Institute of Chemistry, Vietnam Academy of Science and Technology , Hanoi , Vietnam.
Nat Prod Res. 2011 Aug;25(14):1361-5. doi: 10.1080/14786419.2011.569505.
A new dihydrochalcone 4',6'-dihydroxy-2',3',4-trimethoxydihydrochalcone (1) along with nine known compounds, pashanone (2), dihydropashanone (3), pinostrobin (4), 5-hydroxy-7,4'-dimethoxyflavanone (5), 5-hydroxy-6,7-dimethoxyflavanone (6), 5-hydroxy-7,8-dimethoxyflavanone (7), 24-methylencycloartane-3β,21-diol (8), liriodenine (9) and 3,5-dihydroxy-7,3',4'-trimethoxyflavone (10), were isolated from the extracts, exhibiting cytotoxic activity (n-hexane and ethyl acetate extracts) of Miliusa sinensis. The structure of (1) was elucidated by the analysis of spectral data (IR, HR-MS, EI-MS, 1D and 2D NMR).
从中华楠（Miliusa sinensis）提取物中分离得到了一种新的二氢查尔酮化合物 4',6'-二羟基-2',3',4-三甲氧基二氢查尔酮（1）以及其他 9 种已知化合物：pashanone（2）、二氢 pashanone（3）、pinostrobin（4）、5-羟基-7,4'-二甲氧基黄烷酮（5）、5-羟基-6,7-二甲氧基黄烷酮（6）、5-羟基-7,8-二甲氧基黄烷酮（7）、24-甲基环阿屯-3β,21-二醇（8）、利鲁汀（9）和 3,5-二羟基-7,3',4'-三甲氧基黄酮（10）。这些提取物具有细胞毒性活性（正己烷和乙酸乙酯提取物）。通过光谱数据分析（IR、HR-MS、EI-MS、1D 和 2D NMR）阐明了（1）的结构。
