Huong D T, Luong D V, Thao T T P, Sung T V
Institute of Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet road, Cau Giay district, Ha Noi, Viet Nam.
Pharmazie. 2005 Aug;60(8):627-9.
A new flavone named miliufavol [8-(2-hydroxybenzyl)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one or 8-C-(o)-hydroxybenzylpachypodol] from Miliusa balansae (Annonaceae) was isolated and structurally elucidated by spectroscopic means besides four known flavones: ombuine, chrysosplenol B, pachypodol and chrysosplenol C. These flavonoids exhibited interesting cytotoxic activity against three human cell lines (KB, Hep-G2, RD) with IC50 values < 5 microg/ml.
从番荔枝科的巴兰番荔枝（Miliusa balansae）中分离出一种名为米柳黄酮[8-(2-羟基苄基)-5-羟基-2-(4-羟基-3-甲氧基苯基)-3,7-二甲氧基-4H-色原酮-4-酮或8-C-(邻)-羟基苄基厚壳桂醇]的新黄酮，并通过光谱手段对其进行了结构解析，此外还分离出四种已知黄酮：奥布因、金腰醇B、厚壳桂醇和金腰醇C。这些黄酮类化合物对三种人类细胞系（KB、Hep-G2、RD）表现出有趣的细胞毒性活性，IC50值<5微克/毫升。
