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1064nm Q 开关 Nd:YAG 激光治疗太田痣:50 例印度开放性前瞻性研究。

1064 nm Q switched Nd: YAG laser treatment of nevus of Ota: an Indian open label prospective study of 50 patients.

机构信息

Department of Dermatology, STD and Leprosy, Dr. RML Hospital and PGIMER, Baba Kharak Singh Marg, New Delhi 110 001, India.

出版信息

Indian J Dermatol Venereol Leprol. 2011 Sep-Oct;77(5):565-70. doi: 10.4103/0378-6323.84057.

Abstract

BACKGROUND

Nevus of Ota is very common in Asians. Estimated male to female ratio is 1:4.8. Patients seek treatment early in life due to psychological trauma and cosmetic disfigurement. The creation of high power, short pulse Q switched lasers has recently provided tools for considerable therapeutic advances in the treatment of dermal pigmented lesions.

AIMS

To determine the efficacy and side-effect profile of Q switched Nd:YAG Laser (QSNYL) in fifty Indian patients.

METHODS

Fifty patients of nevus of Ota underwent multiple treatments (average 5 sessions) at monthly intervals carried out over a period of 2 years with QSNYL (Med-lite C6). Of the 50 patients, 2 were males; and the rest were females. Skin types treated included phototype IV and V. The response after subsequent treatments was documented through serial photographs that were taken before and after every treatment session. Response to the treatment was graded based on quartile grading scale.

RESULTS

Near total improvement was seen in 8%, marked improvement in 22%, moderate improvement in 38% and 32% patients reported less than 25% clearing of the lesion. All patients reported some improvement. Transient postinflammatory hyperpigmentation was observed in 4 (8%) patients, which cleared with use of sunscreens and bleaching agents within 2 months. No textural change or scarring was observed in any patient.

CONCLUSIONS

QSNYL is an easy-to-perform and effective treatment in cases of nevus of Ota in Indian patients with few side effects.

摘要

背景

太田痣在亚洲人中非常常见。据估计,男女比例为 1:4.8。由于心理创伤和容貌受损,患者在生命早期就寻求治疗。高能量、短脉冲 Q 开关激光的出现,为治疗皮肤色素性病变提供了相当大的治疗进展的工具。

目的

确定 Q 开关 Nd:YAG 激光(QSNYL)在 50 例印度患者中的疗效和副作用情况。

方法

50 例太田痣患者接受了多次治疗(平均 5 次),每月一次,持续 2 年,使用 QSNYL(Med-lite C6)。50 例患者中,男性 2 例,其余为女性。治疗的皮肤类型包括光型 IV 和 V。通过每次治疗前后拍摄的系列照片记录随后治疗的反应。根据四分位分级量表对治疗反应进行分级。

结果

8%的患者有接近完全的改善,22%的患者有明显的改善,38%的患者有中度的改善,32%的患者报告病变清除率低于 25%。所有患者都报告有一定程度的改善。4 例(8%)患者出现短暂的炎症后色素沉着过度,在 2 个月内使用防晒霜和漂白剂后消退。没有患者出现质地改变或疤痕。

结论

QSNYL 是一种易于操作且有效的治疗太田痣的方法,在印度患者中副作用较少。

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