Hepatobiliary and Pancreatic Surgical Unit, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, United Kingdom.
World J Gastrointest Surg. 2011 Jul 27;3(7):101-5. doi: 10.4240/wjgs.v3.i7.101.
To investigate the role of laparoscopy in the surgical management of hepatocellular adenoma (HA).
We reviewed a prospectively collected database of consecutive patients undergoing laparoscopic liver resection for HA.
Thirteen patients underwent fifteen pure laparoscopic liver resections for HA (male/female: 3/10; median age 42 years, range 22-72 years). Two patients with liver adenomatosis required two different laparoscopic operations for ruptured adenomas. Indications for surgery were: symptoms in 12 cases, need to rule out malignancy in 2 cases and preoperative diagnosis of large HA in one case. Symptoms were related to bleeding in 10 cases, sepsis due to liver abscess following embolization of HA in one case and mass effect in one case (shoulder tip pain). Five cases with ruptured bleeding adenoma required emergency admission and treatment with selective arterial embolization. Laparoscopic liver resection was then semi-electively performed. Eight patients (62%) required major hepatectomy [right hepatectomy (n = 5), left hepatectomy (n = 3)]. No conversion to open surgery occurred. The median operative time for pure laparoscopic procedures was 270 min (range 135-360 min). The median size of the excised lesions was 85 mm (range 25-180 mm). One patient with adenomatosis developed postoperative bleeding requiring embolization. Mortality was nil. The median hospital stay was 4 d (range 1-18 d) with a median high dependency unit stay of 1 d (range 0-7 d).
The laparoscopic approach represents a safe option for the management of HA in a semi-elective setting and when major hepatectomy is required.
探讨腹腔镜在肝细胞腺瘤(HA)外科治疗中的作用。
我们回顾了连续接受腹腔镜肝切除术治疗 HA 的患者的前瞻性收集数据库。
13 例患者接受了 15 例纯腹腔镜肝切除术治疗 HA(男/女:3/10;中位年龄 42 岁,范围 22-72 岁)。2 例肝腺瘤病患者因破裂腺瘤需要进行两次不同的腹腔镜手术。手术适应证为:12 例有症状,2 例需要排除恶性肿瘤,1 例术前诊断为大 HA。症状与出血有关的有 10 例,1 例因 HA 栓塞后肝脓肿导致脓毒症,1 例因肩部疼痛导致占位效应。5 例破裂出血腺瘤患者需要紧急入院治疗,并进行选择性动脉栓塞。然后半择期进行腹腔镜肝切除术。8 例(62%)需要进行大肝切除术[右半肝切除术(n=5),左半肝切除术(n=3)]。没有转为开放性手术。纯腹腔镜手术的中位手术时间为 270 分钟(范围 135-360 分钟)。切除病灶的中位大小为 85 毫米(范围 25-180 毫米)。1 例腺瘤病患者术后发生出血,需要栓塞治疗。无死亡病例。中位住院时间为 4 天(范围 1-18 天),中位高依赖病房停留时间为 1 天(范围 0-7 天)。
在半择期和需要进行大肝切除术的情况下,腹腔镜方法是治疗 HA 的安全选择。