使用带有 4,5-二氮菲配体的钯催化剂进行吲哚和苯的区域控制有氧氧化偶联。
Regiocontrolled aerobic oxidative coupling of indoles and benzene using Pd catalysts with 4,5-diazafluorene ligands.
机构信息
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA.
出版信息
Chem Commun (Camb). 2011 Oct 7;47(37):10257-9. doi: 10.1039/c1cc13632a. Epub 2011 Aug 22.
Abstract
Palladium-catalyzed aerobic oxidative cross-couplings of indoles and benzene have been achieved by using 4,5-diazafluorene derivatives as ancillary ligands. Proper choice of the neutral and anionic ligands enables control over the reaction regioselectivity.
摘要
钯催化吲哚和苯的有氧氧化交叉偶联反应已通过使用 4,5-二氮杂芴衍生物作为辅助配体来实现。通过选择合适的中性和阴离子配体，可以控制反应的区域选择性。
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