Doctoral degree, speech therapy at the Núcleo do Ouvido Biônico (Bionic Ear Center), São Paulo Samaritan Hospital.
Full professor, São Paulo University.
Braz J Otorhinolaryngol. 2011 Jul-Aug;77(4):481-487. doi: 10.1590/S1808-86942011000400012.
The electrical stimulation generated by the Cochlear Implant (CI) may improve the neural synchrony and hence contribute to the development of auditory skills in patients with Auditory Neuropathy/Auditory Dyssynchrony (AN/AD).
Prospective cohort cross-sectional study to evaluate the auditory performance and the characteristics of the electrically evoked compound action potential (ECAP) in 18 children with AN/AD and cochlear implants.
The auditory perception was evaluated by sound field thresholds and speech perception tests. To evaluate ECAP's characteristics, the threshold and amplitude of neural response were evaluated at 80 Hz and 35 Hz.
No significant statistical difference was found concerning the development of auditory skills. The ECAP's characteristics differences at 80 and 35 Hz stimulation rate were also not statistically significant.
The CI was seen as an efficient resource to develop auditory skills in 94% of the AN/AD patients studied. The auditory perception benefits and the possibility to measure ECAP showed that the electrical stimulation could compensate for the neural dyssynchrony caused by the AN/AD. However, a unique clinical procedure cannot be proposed at this point. Therefore, a careful and complete evaluation of each AN/AD patient before recommending a Cochlear Implant is advised. Clinical Trials: NCT01023932.
耳蜗植入物（CI）产生的电刺激可能会改善神经同步性，从而有助于患有听神经病/听神经不同步（AN/AD）的患者发展听觉技能。
前瞻性队列交叉研究评估 18 例 AN/AD 伴耳蜗植入患者的听觉表现和电诱发复合动作电位（ECAP）的特征。
通过声场阈值和言语感知测试评估听觉感知。为了评估 ECAP 的特征，在 80 Hz 和 35 Hz 的刺激率下评估神经反应的阈值和幅度。
关于听觉技能的发展，未发现统计学差异。80 和 35 Hz 刺激率下的 ECAP 特征差异也无统计学意义。
CI 被视为开发 94%所研究的 AN/AD 患者听觉技能的有效资源。听觉感知益处和测量 ECAP 的可能性表明，电刺激可以补偿 AN/AD 引起的神经不同步。然而，目前还不能提出一种独特的临床程序。因此，建议在推荐耳蜗植入之前，对每位 AN/AD 患者进行仔细和全面的评估。临床试验：NCT01023932。
