在听觉保健服务中听觉神经病谱障碍的流行率。
Prevalence of auditory neuropathy spectrum disorder in an auditory health care service.
机构信息
School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.
出版信息
Braz J Otorhinolaryngol. 2013 Aug;79(4):429-33. doi: 10.5935/1808-8694.20130077.
UNLABELLED
Auditory neuropathy spectrum disorder (ANSD) is characterized by impairment of the auditory nerve associated with preservation of outer hair cell function.
OBJECTIVE
To establish the prevalence of ANSD in subjects with sensorineural hearing loss (SNHL).
METHOD
This retrospective study was carried out between 2010 and 2012 and included the charts of 2,292 individuals with SNHL. Data from otolaryngological and audiological examinations based on pure-tone and speech audiometry, impedance tests, otoacoustic emissions (OAEs), and brainstem auditory evoked potentials (BAEPs) were collected.
INCLUSION CRITERIA
presence of OAEs and/or cochlear microphonic (CM); absent or altered BAEPs, and normal MRI scans of the brain.
RESULTS
Twenty-seven (1.2%) of the 2,292 subjects with SNHL had ANSD (37% males; 63% females). Mild SNHL was seen in 29.6% of the individuals with ANSD; 55.5% had moderate SNHL; 7.4% had severe SNHL; and 7.5% had profound SNHL. In terms of age, 14.8% were aged between zero and 20 years, 44.1% were 41 to 60 years old, and 7.4% were above the age of 60.
CONCLUSION
ANSD was seen in 1.2% of the individuals with SNHL included in this study.
未加标签
听觉神经病谱系障碍（ANSD）的特征是与外毛细胞功能保留相关的听神经损伤。
目的
确定感音神经性听力损失（SNHL）患者中 ANSD 的患病率。
方法
这是一项回顾性研究，于 2010 年至 2012 年进行，共纳入 2292 名 SNHL 患者的病历。收集了纯音和言语测听、阻抗测试、耳声发射（OAE）和脑干听觉诱发电位（BAEP）等听力学检查以及耳鼻喉科检查的数据。
纳入标准
存在 OAE 和/或耳蜗微音（CM）；BAEP 缺失或改变，且脑磁共振成像（MRI）正常。
结果
2292 名 SNHL 患者中有 27 名（1.2%）患有 ANSD（男性占 37%；女性占 63%）。ANSD 患者中有 29.6%为轻度 SNHL；55.5%为中度 SNHL；7.4%为重度 SNHL；7.5%为极重度 SNHL。就年龄而言，14.8%的患者年龄在 0 至 20 岁之间，44.1%的患者年龄在 41 至 60 岁之间，7.4%的患者年龄在 60 岁以上。
结论
在本研究纳入的 SNHL 患者中，ANSD 的患病率为 1.2%。
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