Chwalek Jennifer, Goldberg David J
Curr Probl Dermatol. 2011;42:40-47. doi: 10.1159/000328243. Epub 2011 Aug 16.
Ablative skin resurfacing has remained the gold standard for treating photodamage and acne scars since the development of the first CO(2) lasers. CO(2) and Er:YAG lasers emit infrared light, which targets water resulting in tissue contraction and collagen formation. The first ablative laser systems created significant thermal damage resulting in unacceptably high rates of scarring and prolonged healing. Newer devices, such as high-energy pulsed lasers and fractional ablative lasers, are capable of achieving significant improvements with fewer side effects and shorter recovery times. While ablative resurfacing has become safer, careful patient selection is still important to avoid post-treatment scarring, dyspigmentation, and infections. Clinicians utilizing ablative devices need to be aware of possible side effects in order to maximize results and patient satisfaction. This chapter reviews the background of ablative lasers including the types of ablative lasers, mechanism of action, indications for ablative resurfacing, and possible side effects.
自第一代二氧化碳激光问世以来,剥脱性皮肤重建一直是治疗光损伤和痤疮瘢痕的金标准。二氧化碳激光和铒钇铝石榴石激光发射红外光,其作用于水,导致组织收缩和胶原蛋白形成。第一代剥脱性激光系统造成了严重的热损伤,导致瘢痕形成率高得令人无法接受且愈合时间延长。新型设备,如高能脉冲激光和分次剥脱性激光,能够在副作用更少、恢复时间更短的情况下取得显著改善。虽然剥脱性重建已变得更安全,但谨慎选择患者对于避免治疗后瘢痕形成、色素沉着和感染仍很重要。使用剥脱性设备的临床医生需要了解可能的副作用,以便最大限度地提高治疗效果和患者满意度。本章回顾了剥脱性激光的背景,包括剥脱性激光的类型、作用机制、剥脱性重建的适应证以及可能的副作用。