Walling M, Andersen B L, Johnson S R
Department of Psychology, University of Iowa, Iowa City 52242.
Arch Sex Behav. 1990 Apr;19(2):119-37. doi: 10.1007/BF01542227.
The impact of hormonal replacement therapy on sexual behavior and functioning in postmenopausal women was examined. A methodological overview discusses issues of subject characteristics, research design, and the assessment of sexual functioning and related outcomes. Current therapy regimens include estrogen, progestogen, androgen, and combination therapy (e.g., cyclic estrogen and progestogen). With estrogen, significant gynecologic improvement (i.e., reduction in atrophic vaginitis) occurs, and this may in turn provide the context for sexual activity/functioning to proceed unimpaired. Although there are medical indications for the addition of progestogen to an estrogen regimen, there appear to be no improvements in sexual functioning beyond those that occur with estrogen alone. Finally, androgen may affect sexual functioning for specific subgroups of postmenopausal women (i.e., surgically postmenopausal rather than naturally postmenopausal women).
研究了激素替代疗法对绝经后女性性行为和性功能的影响。一篇方法学综述讨论了受试者特征、研究设计以及性功能和相关结果评估等问题。目前的治疗方案包括雌激素、孕激素、雄激素以及联合治疗（如周期性雌激素和孕激素）。使用雌激素后，妇科症状有显著改善（即萎缩性阴道炎减轻），这反过来可能为性活动/性功能不受损害地进行提供条件。尽管有医学指征表明在雌激素治疗方案中添加孕激素，但性功能的改善似乎并不超过单独使用雌激素时的改善。最后，雄激素可能对特定亚组的绝经后女性（即手术绝经而非自然绝经的女性）的性功能有影响。
