Pluck Graham, Brown Richard G
Academic Clinical Psychiatry, The University of Sheffield, The Longley Centre, Norwood Grange Drive, Sheffield S5 7JT, UK.
Depress Res Treat. 2011;2011:893873. doi: 10.1155/2011/893873. Epub 2011 Aug 18.
Parkinson's disease (PD) patients display low novelty seeking scores on the Tridimensional Personality Questionnaire (TPQ), which may reflect the low dopamine function that characterises the disease. People with PD also display raised harm avoidance scores. Due to these and other observations, a "parkinsonian personality" has been suggested. However, little is known about how these features relate to cognitive and affective disorders, which are also common in PD. We examined links between TPQ scores and performance on an attentional orienting task in a sample of 20 people with PD. In addition, associations between TPQ and depression and anxiety scores were explored. It was found that novelty seeking scores were significantly correlated with a reaction time measure of attentional orienting to visual novelty. Harm avoidance scores were significantly correlated with anxiety, but not depression scores. These findings extend our understanding of how temperament interacts with cognitive and affective features of the disorder.
帕金森病（PD）患者在三维人格问卷（TPQ）上的新奇寻求得分较低，这可能反映了该疾病所特有的多巴胺功能低下。帕金森病患者的伤害回避得分也较高。基于这些以及其他观察结果，有人提出了“帕金森式人格”。然而，对于这些特征如何与认知和情感障碍相关联，人们知之甚少，而认知和情感障碍在帕金森病中也很常见。我们在20名帕金森病患者的样本中，研究了TPQ得分与注意力定向任务表现之间的联系。此外，还探讨了TPQ与抑郁和焦虑得分之间的关联。研究发现，新奇寻求得分与对视觉新奇事物的注意力定向反应时间测量值显著相关。伤害回避得分与焦虑显著相关，但与抑郁得分无关。这些发现扩展了我们对气质如何与该疾病的认知和情感特征相互作用的理解。
