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白藜芦醇在冠状动脉疾病防治中的作用。

Resveratrol in the prevention and treatment of coronary artery disease.

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Curr Atheroscler Rep. 2011 Dec;13(6):439-46. doi: 10.1007/s11883-011-0202-3.

Abstract

Resveratrol is a polyphenolic compound found in red wine that is believed to be responsible for its beneficial cardiovascular effects. Extensive research in the past several decades has identified multiple mechanisms by which resveratrol modifies the cardiovascular risk factors that lead to coronary artery disease, yet translation to the clinical arena has been unexpectedly slow. In this article, we review the existing evidence regarding the beneficial effects of resveratrol and briefly discuss its potential therapeutic applications.

摘要

白藜芦醇是一种存在于红酒中的多酚化合物,被认为是其对心血管有益的原因。在过去几十年中,广泛的研究已经确定了白藜芦醇改变导致冠状动脉疾病的心血管风险因素的多种机制,但向临床领域的转化却出人意料地缓慢。本文综述了关于白藜芦醇有益作用的现有证据,并简要讨论了其潜在的治疗应用。

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