Glaucoma Division, Jules Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
Graefes Arch Clin Exp Ophthalmol. 2011 Nov;249(11):1593-616. doi: 10.1007/s00417-011-1787-5. Epub 2011 Aug 26.
Detection of visual field progression remains a challenging task despite the recent advances for better handling of longitudinal visual field data, some of which are incorporated in currently available perimeters. Standard achromatic perimetry remains the gold standard for detection of visual field progression. The authors present a practical and clinically relevant review of the main issues involved in detection of early glaucoma as well as detection of visual field progression in eyes with pre-existing glaucomatous damage. After discussing some basic concepts in perimetry, the authors present evidence-based recommendations for criteria to detect earliest evidence of glaucomatous damage with perimetry. The authors will review different event- and trend-based criteria and present data with regard to comparative performance of such criteria. Relevance of using absolute versus corrected threshold data with regard to different criteria is also addressed. At the end, the authors provide practical guidelines for detection of visual field progression in a clinical setting and review issues related to clinical trials.
尽管最近在更好地处理纵向视野数据方面取得了一些进展，其中一些已经纳入了现有的视野计中，但检测视野进展仍然是一项具有挑战性的任务。标准的无色视野检查仍然是检测视野进展的金标准。作者对涉及早期青光眼检测以及已有青光眼损害眼视野进展检测的主要问题进行了实用且与临床相关的综述。在讨论了视野检查中的一些基本概念之后，作者提出了基于循证的建议，以确定使用视野检查检测青光眼最早损害的标准。作者将回顾不同的基于事件和趋势的标准，并提供有关此类标准的比较性能的数据。还讨论了在不同标准中使用绝对阈值数据与校正阈值数据的相关性。最后，作者提供了在临床环境中检测视野进展的实用指南，并回顾了与临床试验相关的问题。
