Miki Atsuya
Hamilton Glaucoma Center, University of California, San Diego.
J Curr Glaucoma Pract. 2012 May-Aug;6(2):62-67. doi: 10.5005/jp-journals-10008-1108. Epub 2012 Aug 16.
To provide an update on the role of optic nerve head and peripapillary retinal nerve fiber layer imaging in monitoring glaucoma progression.
Review of literature.
Imaging technologies, such as optical coherence tomography, scanning laser polarimetry, and confocal scanning laser ophthalmoscopy, objectively and quantitatively measure the structural change associated with glaucoma. Rates of retinal nerve fiber layer (RNFL) and rim area loss are significantly faster in progressing compared with nonprogressing subjects. A number of strategies to detect progression have been proposed. The precision of these methods is generally high. However, there is no agreement as to which instrument or parameter is most appropriate for the evaluation of structural progression associated with glaucoma at this moment. The agreement between structural and functional glaucoma progression is generally poor regardless of the strategies used. Structural progression analyses appear to complement visual field progression analyses, detecting a different subset of progressing subjects.
Imaging devices are promising tools for monitoring patients with glaucoma. Combining structural and functional analyses is useful for accurate monitoring of glaucoma progression.
Miki A. Assessment of Structural Glaucoma Progression. J Current Glau Prac 2012;6(2):62-67.
提供关于视神经乳头和视乳头周围视网膜神经纤维层成像在监测青光眼进展中作用的最新信息。
文献综述。
光学相干断层扫描、扫描激光偏振仪和共焦扫描激光检眼镜等成像技术可客观、定量地测量与青光眼相关的结构变化。与病情无进展的受试者相比,进展期受试者的视网膜神经纤维层(RNFL)和视盘边缘面积丢失率明显更快。已经提出了多种检测进展的策略。这些方法的精度一般较高。然而,目前对于哪种仪器或参数最适合评估与青光眼相关的结构进展尚无定论。无论采用何种策略,青光眼结构进展与功能进展之间的一致性通常较差。结构进展分析似乎可补充视野进展分析,检测出病情进展的不同亚组受试者。
成像设备是监测青光眼患者的有前景的工具。结合结构和功能分析有助于准确监测青光眼进展。
Miki A. 青光眼结构进展的评估。《J Current Glau Prac》2012;6(2):62 - 67。