Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Sleep Med. 2011 Sep;12(8):797-9. doi: 10.1016/j.sleep.2010.12.020. Epub 2011 Aug 25.
Determine whether obstructive sleep apnea (OSA) is associated with the dietary choices of obese individuals during middle- to late-childhood. It was hypothesized that OSA would be associated with increased caloric content of a dinner order, particularly with high carbohydrate food choices. Secondarily, we examined the relationships between sleep duration and dietary choices.
42 obese subjects aged 10-16.9 years participated in a cross-sectional study that involved systematic collection of sleep duration (based on actigraphy), presence and severity of obstructive sleep apnea (obstructive apnea+hypopnea index [AHI] from inpatient polysomnography) and the macronutrient content of dinners ordered from a standardized hospital menu the evening before the polysomnogram.
Primary analyses using Spearman rank-order correlations found that AHI was significantly associated with total calories, as well as grams of fat and carbohydrate, but not protein. These macronutrient variables did not correlate with sleep duration across a week, nor the night before the meal. Findings were unchanged after correcting for age- and sex-adjusted BMI.
More severe OSA appears to be associated with an increased preference for calorie-dense foods that are high in fat and carbohydrates in a manner that is independent of degree of obesity. Although this novel finding awaits replication, it has potential implications for the clinical care of obese youth and individuals with OSA, adds to the limited data that relate sleep to dietary choices and may have implications for OSA-related morbidity.
确定阻塞性睡眠呼吸暂停（OSA）是否与肥胖个体在中晚期儿童期的饮食选择有关。假设 OSA 与晚餐订单的热量含量增加有关，特别是与高碳水化合物食物的选择有关。其次，我们研究了睡眠持续时间与饮食选择之间的关系。
42 名年龄在 10-16.9 岁的肥胖受试者参加了一项横断面研究，该研究涉及系统地收集睡眠持续时间（基于活动记录仪）、阻塞性睡眠呼吸暂停的存在和严重程度（住院多导睡眠图上的阻塞性呼吸暂停+低通气指数[AHI]）以及前一天晚上从标准化医院菜单中订购的晚餐的宏量营养素含量。
使用 Spearman 等级相关分析的主要分析发现，AHI 与总卡路里以及脂肪和碳水化合物的克数显著相关，但与蛋白质无关。这些宏量营养素变量与一周内的睡眠持续时间或用餐前一晚的睡眠持续时间没有相关性。在对年龄和性别调整后的 BMI 进行校正后，结果仍然不变。
更严重的 OSA 似乎与高热量、高脂肪和高碳水化合物的食物偏好增加有关，这种情况与肥胖程度无关。尽管这一新颖的发现有待进一步证实，但它对肥胖青少年和 OSA 患者的临床护理具有潜在影响，增加了与睡眠与饮食选择相关的有限数据，并可能对与 OSA 相关的发病率产生影响。
