用于肌腱和韧带损伤的细胞疗法。

Cell-based therapies for tendon and ligament injuries.

作者信息

Alves A G L, Stewart Allison A, Dudhia J, Kasashima Y, Goodship A E, Smith R K W

机构信息

Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University, Botucatu, São Paulo 18618970, Brazil.

出版信息

Vet Clin North Am Equine Pract. 2011 Aug;27(2):315-33. doi: 10.1016/j.cveq.2011.06.001.

DOI:10.1016/j.cveq.2011.06.001

PMID:21872761

Abstract

Tendon and ligament injuries have proved difficult to treat effectively. Cell-based therapies offer the potential to harness the complex protein synthetic machinery of the cell to induce a regenerative response rather than fibrous scarring. This article reviews the current state of play with respect to the clinically used cell preparations for the treatment of tendon and ligaments overstrain injuries.

摘要

事实证明，肌腱和韧带损伤难以得到有效治疗。基于细胞的疗法有可能利用细胞复杂的蛋白质合成机制来诱导再生反应，而非纤维瘢痕形成。本文综述了目前临床上用于治疗肌腱和韧带过度劳损损伤的细胞制剂的进展情况。