Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences (IVF, CAAS), Beijing, China.
Nat Genet. 2011 Aug 28;43(10):1035-9. doi: 10.1038/ng.919.
We report the annotation and analysis of the draft genome sequence of Brassica rapa accession Chiifu-401-42, a Chinese cabbage. We modeled 41,174 protein coding genes in the B. rapa genome, which has undergone genome triplication. We used Arabidopsis thaliana as an outgroup for investigating the consequences of genome triplication, such as structural and functional evolution. The extent of gene loss (fractionation) among triplicated genome segments varies, with one of the three copies consistently retaining a disproportionately large fraction of the genes expected to have been present in its ancestor. Variation in the number of members of gene families present in the genome may contribute to the remarkable morphological plasticity of Brassica species. The B. rapa genome sequence provides an important resource for studying the evolution of polyploid genomes and underpins the genetic improvement of Brassica oil and vegetable crops.
我们报告了甘蓝型油菜品种 Chiifu-401-42 草案基因组序列的注释和分析。我们对甘蓝型油菜基因组中的 41174 个蛋白质编码基因进行了建模，该基因组经历了基因组三倍化。我们使用拟南芥作为外类群来研究基因组三倍化的后果，例如结构和功能进化。在三倍化基因组片段中，基因丢失（分化）的程度不同，其中三个拷贝之一始终保持了不成比例的大量预期存在于其祖先中的基因。基因组中存在的基因家族成员数量的变化可能有助于甘蓝型物种的显著形态可塑性。甘蓝型油菜基因组序列为研究多倍体基因组的进化提供了重要资源，并为甘蓝型油菜油用和蔬菜作物的遗传改良奠定了基础。
