Turssi Cecilia P, Maeda Fernando A, Messias Danielle C F, Neto Francisco C Rehder, Serra Mônica C, Galafassi Daniel
Instituto e Centro de Pesquisas São Leopoldo Mandic, Laboratório de Ensaio de Materiais, SP, Brazil.
Am J Dent. 2011 Jun;24(3):165-8.
To assess whether pastes containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and calcium sodium phosphosilicate (CSP) protect acid softened enamel against further erosive episodes.
Enamel slabs of bovine teeth with preformed erosion-like lesions were randomly assigned to five treatment groups (n = 15): A) CPP-ACP (MI Paste, GC America); B) CPP-ACP+Fluoride (CPP-ACP+F, MI Plus Paste, GC America); C) CSP (Tooth Revitalizing Paste, Oravive); D) fluoridated dentifrice (FD, Sensodyne Cool Gel, GSK); E) control (CO, unexposed to any product). Paste treatments (1:3 slurry in deionized water or undiluted product in the case of the CPP-ACP formulae) were performed between five cycles of alternating erosive challenge (0.3% citric acid, pH = 3.2) and remineralization in artificial saliva. Specimens were analyzed by Knoop surface microhardness (SMH).
ANOVA indicated a significant (P< 0.0001) difference among the SMH values attained by acid softened enamel following the exposure to the pastes interspersed with erosion-remineralization cycles. Tukey's test ascertained that SMH values observed for the CPP-ACP+F and CSP groups did not differ from that of FD group, which were significantly higher than that found for the CO group. Specimens treated with CPP-ACP did not differ from any of the other groups.
评估含有酪蛋白磷酸肽 - 无定形磷酸钙（CPP - ACP）和磷酸硅钙钠（CSP）的糊剂是否能保护酸软化牙釉质免受进一步的侵蚀。
将具有预先形成的类似侵蚀性病变的牛牙釉质块随机分为五个治疗组（n = 15）：A）CPP - ACP（MI糊剂，GC America）；B）CPP - ACP + 氟化物（CPP - ACP + F，MI Plus糊剂，GC America）；C）CSP（牙齿焕活糊剂，Oravive）；D）含氟牙膏（FD，舒适达清凉啫喱，葛兰素史克）；E）对照组（CO，未接触任何产品）。在五个交替的侵蚀性挑战（0.3％柠檬酸，pH = 3.2）和人工唾液再矿化循环之间进行糊剂处理（对于CPP - ACP配方，在去离子水中制成1:3的浆液或未稀释的产品）。通过努氏表面显微硬度（SMH）分析样本。
方差分析表明，在经历侵蚀 - 再矿化循环并接触糊剂后，酸软化牙釉质所获得的SMH值之间存在显著差异（P < 0.0001）。Tukey检验确定，CPP - ACP + F组和CSP组观察到的SMH值与FD组无差异，FD组的值显著高于CO组。用CPP - ACP处理的样本与其他任何组均无差异。
