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老年急诊临床药理学

Geriatric emergency clinical pharmacology.

作者信息

Fox F J, Auestad A E

机构信息

Department of Emergency Medicine, Childrens' Hospital, San Francisco, California.

出版信息

Emerg Med Clin North Am. 1990 May;8(2):221-39.

PMID:2187679
Abstract

Drugs associated with elderly individuals seen in the Emergency Department must be understood both as causal or etiologic agents of certain common presentations and as therapeutic tools. Special problems of the elderly include their increased frequency and altered patterns of drug use as compared with younger persons. They are predisposed to problems with certain drugs because of altered hepatic blood flow, renal clearance, body composition, sensitivities, and compliance that result from age. Most important, the practitioner is now provided with a set of resources, including lists of common presentations in the Emergency Department and specific drugs that must be considered to be potential etiologic or causative agents for that presentation. In addition, therapeutic agents for both physicians and elderly patients are presented in catechism.

摘要

在急诊科见到的与老年人相关的药物,必须既被理解为某些常见症状的病因或致病因素,又被理解为治疗工具。老年人的特殊问题包括与年轻人相比,他们用药的频率增加且用药模式改变。由于年龄导致的肝血流量、肾清除率、身体组成、敏感性和依从性改变,他们更容易出现某些药物相关的问题。最重要的是,从业者现在有了一系列资源,包括急诊科常见症状清单以及必须被视为该症状潜在病因或致病因素的特定药物清单。此外,还以问答形式介绍了医生和老年患者可用的治疗药物。

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The epidemiology of serious adverse drug reactions among the elderly.老年人严重药物不良反应的流行病学
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