Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane 4059, Australia.
Eur J Appl Physiol. 2012 May;112(5):1963-6. doi: 10.1007/s00421-011-2143-5. Epub 2011 Aug 30.
The aim of this study was to determine the intraocular pressure response to differing levels of dehydration. Seven males participated in 90 min of treadmill walking (5 km h(-1) and 1% grade) in both temperate (22 °C) and hot (43 °C) conditions. At baseline and 30 min intervals intraocular pressure, nude body mass, body temperature and heart rate were recorded. Statistically significant interactions (p < 0.05) were observed for intraocular pressure (hot condition: baseline 17.0 ± 2.9, 30 min 15.6 ± 3.5, 60 min 14.5 ± 3.7 and 90 min 13.6 ± 2.9 mmHg; temperate condition: baseline 16.8 ± 2.7, 30 min 16.5 ± 2.6, 60 min 15.8 ± 2.5 and 90 min 15.7 ± 1.8 mmHg) and body mass loss (hot condition: 30 min -1.07 ± 0.35, 60 min -2.17 ± 0.55 and 90 min -3.13 ± 0.74%; temperate condition: 30 min -0.15 ± 0.11, 60 min -0.47 ± 0.18 and 90 min -0.78 ± 0.25%). Significant linear regressions (p < 0.05) were observed for intraocular pressure and body mass loss (adjusted r(2) = 0.24) and intraocular pressure change and body mass loss (adjusted r(2) = 0.51). In conclusion, intraocular pressure was progressively reduced during a period of exercise causing dehydration, but remained relatively stable when hydration was maintained. The present study revealed a moderate relationship between dehydration (body mass loss) and intraocular pressure change.
本研究旨在确定不同程度脱水对眼内压的影响。7 名男性在温带（22°C）和热环境（43°C）下分别进行 90 分钟的跑步机行走（5km/h 和 1%坡度）。在基线和 30 分钟间隔内，记录眼内压、裸体体重、体温和心率。观察到眼内压（热环境：基线 17.0±2.9mmHg，30 分钟 15.6±3.5mmHg，60 分钟 14.5±3.7mmHg 和 90 分钟 13.6±2.9mmHg；温带环境：基线 16.8±2.7mmHg，30 分钟 16.5±2.6mmHg，60 分钟 15.8±2.5mmHg 和 90 分钟 15.7±1.8mmHg）和体重损失（热环境：30 分钟-1.07±0.35%，60 分钟-2.17±0.55%和 90 分钟-3.13±0.74%；温带环境：30 分钟-0.15±0.11%，60 分钟-0.47±0.18%和 90 分钟-0.78±0.25%）存在显著的交互作用（p<0.05）。眼内压和体重损失（调整 r(2)=0.24）以及眼内压变化和体重损失（调整 r(2)=0.51）之间存在显著的线性回归（p<0.05）。结论：在导致脱水的运动过程中，眼内压逐渐降低，但在保持水合状态时相对稳定。本研究揭示了脱水（体重损失）和眼内压变化之间的中度关系。
