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用于宫颈筛查的 cobas 4800 HPV 检测的临床验证。

Clinical validation of the cobas 4800 HPV test for cervical screening purposes.

机构信息

Department of Pathology, VU University Medical Center, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

出版信息

J Clin Microbiol. 2011 Nov;49(11):3983-5. doi: 10.1128/JCM.05552-11. Epub 2011 Aug 31.

DOI:10.1128/JCM.05552-11
PMID:21880968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3209101/
Abstract

This study shows that the clinical performance and reproducibility of the cobas 4800 HPV test for high-risk human papillomavirus (HPV) detection fulfill the criteria as formulated in international guidelines of HPV test requirements for cervical screening purposes. Accordingly, the cobas 4800 HPV test can be considered clinically validated for cervical screening.

摘要

本研究表明，cobas 4800 HPV 检测用于高危型人乳头瘤病毒（HPV）检测的临床性能和可重复性符合国际 HPV 检测用于宫颈癌筛查要求指南中规定的标准。因此，cobas 4800 HPV 检测可被视为用于宫颈癌筛查的临床验证。

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本文引用的文献

1
[Evaluation of a prototype real-time PCR assay for the separate detection of human papilloma virus genotypes 16 and 18 and other high risk human papillomavirus in cervical cancer screening].[用于宫颈癌筛查中单独检测人乳头瘤病毒16型和18型及其他高危人乳头瘤病毒的实时PCR检测原型评估]
Enferm Infecc Microbiol Clin. 2011 Jun-Jul;29(6):411-4. doi: 10.1016/j.eimc.2011.01.007. Epub 2011 Mar 23.
2
Evaluation of 14 triage strategies for HPV DNA-positive women in population-based cervical screening.基于人群的宫颈癌筛查中 HPV DNA 阳性女性的 14 种分诊策略评估。
Int J Cancer. 2012 Feb 1;130(3):602-10. doi: 10.1002/ijc.26056. Epub 2011 May 5.
3
High-risk human papillomavirus testing in women with ASC-US cytology: results from the ATHENA HPV study.人乳头瘤病毒高危型检测在 ASC-US 细胞学检查中的应用：ATHENA HPV 研究结果。
Am J Clin Pathol. 2011 Mar;135(3):468-75. doi: 10.1309/AJCPZ5JY6FCVNMOT.
4
Validation of high-risk HPV tests for primary cervical screening.高危型 HPV 检测用于宫颈癌初筛的验证。
J Clin Virol. 2009 Nov;46 Suppl 3:S1-4. doi: 10.1016/S1386-6532(09)00540-X.
5
Comparison of HPV and cytology triage algorithms for women with borderline or mild dyskaryosis in population-based cervical screening (VUSA-screen study).基于人群的宫颈筛查中，对边界性或轻度不典型鳞状上皮细胞（ASC-US）的女性，HPV 和细胞学分流算法的比较（VUSA-screen 研究）。
Int J Cancer. 2010 May 1;126(9):2175-81. doi: 10.1002/ijc.24891.
6
Evaluation of a prototype real-time PCR assay for carcinogenic human papillomavirus (HPV) detection and simultaneous HPV genotype 16 (HPV16) and HPV18 genotyping.评价一种用于致癌型人乳头瘤病毒（HPV）检测和同时进行 HPV16（人乳头瘤病毒 16 型）和 HPV18 基因型分型的实时 PCR 检测方法的原型。
J Clin Microbiol. 2009 Oct;47(10):3344-7. doi: 10.1128/JCM.00725-09. Epub 2009 Aug 12.
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Guidelines for human papillomavirus DNA test requirements for primary cervical cancer screening in women 30 years and older.30岁及以上女性原发性宫颈癌筛查中人乳头瘤病毒DNA检测要求指南。
Int J Cancer. 2009 Feb 1;124(3):516-20. doi: 10.1002/ijc.24010.
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GP5+/6+ PCR followed by reverse line blot analysis enables rapid and high-throughput identification of human papillomavirus genotypes.采用通用引物5+/6+聚合酶链反应（GP5+/6+ PCR），随后进行反向线印迹分析，能够快速、高通量地鉴定人乳头瘤病毒基因型。
J Clin Microbiol. 2002 Mar;40(3):779-87. doi: 10.1128/JCM.40.3.779-787.2002.