A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood.
作者信息
Peng Hanjing, Cheng Yunfeng, Dai Chaofeng, King Adrienne L, Predmore Benjamin L, Lefer David J, Wang Binghe
机构信息
Department of Chemistry, and Center for Biotechnology and Drug Design, Georgia State University, P.O. Box 4098, Atlanta, GA 30302-4098, USA.
出版信息
Angew Chem Int Ed Engl. 2011 Oct 4;50(41):9672-5. doi: 10.1002/anie.201104236. Epub 2011 Aug 31.
Abstract
摘要
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Hydrogen sulphide: novel opportunity for drug discovery.硫化氢：药物研发的新机遇。
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2
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.遗传和药理学硫化氢治疗可减轻小鼠缺血性心力衰竭。
Circulation. 2010 Jul 6;122(1):11-9. doi: 10.1161/CIRCULATIONAHA.109.920991. Epub 2010 Jun 21.
3
Making and working with hydrogen sulfide: The chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review.制备和应用硫化氢：硫化氢的体外化学合成和作用及其体内测量：综述。
Free Radic Biol Med. 2009 Nov 15;47(10):1346-53. doi: 10.1016/j.freeradbiomed.2009.09.018. Epub 2009 Sep 19.
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Hydrogen sulfide mediates cardioprotection through Nrf2 signaling.硫化氢通过Nrf2信号通路介导心脏保护作用。
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Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values.全组织硫化氢浓度比目前公认的值低几个数量级。
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Reappraisal of H2S/sulfide concentration in vertebrate blood and its potential significance in ischemic preconditioning and vascular signaling.脊椎动物血液中H2S/硫化物浓度的重新评估及其在缺血预处理和血管信号传导中的潜在意义。
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A new gaseous signaling molecule emerges: cardioprotective role of hydrogen sulfide.一种新的气体信号分子出现了：硫化氢的心脏保护作用。
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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.硫化氢通过维持线粒体功能减轻心肌缺血再灌注损伤。
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Endogenous hydrogen sulfide in patients with COPD.慢性阻塞性肺疾病患者体内的内源性硫化氢
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