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Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies.

作者信息

Inaba Hiroto, Bhojwani Deepa, Pauley Jennifer L, Pei Deqing, Cheng Cheng, Metzger Monika L, Howard Scott C, Rubnitz Jeffrey E, Sandlund John T, Ribeiro Raul C, Leung Wing, Campana Dario, Pui Ching-Hon, Jeha Sima

出版信息

Br J Haematol. 2012 Jan;156(2):275-9. doi: 10.1111/j.1365-2141.2011.08847.x. Epub 2011 Aug 25.

DOI:10.1111/j.1365-2141.2011.08847.x
PMID:21883141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3235268/
Abstract
摘要

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Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies.氯法拉滨、环磷酰胺和依托泊苷联合化疗用于难治性或复发性血液系统恶性肿瘤儿童患者
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2
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.一项关于克拉屈滨、依托泊苷和环磷酰胺联合治疗难治性或复发性急性白血病患儿的多中心 I 期研究。
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3
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Clofarabine in Pediatric Acute Relapsed or Refractory Leukemia: Where Do We Stand on the Bridge to Hematopoietic Stem Cell Transplantation?氯法拉滨用于小儿急性复发或难治性白血病：在通往造血干细胞移植之路上我们处于什么位置？
J Hematol. 2023 Feb;12(1):16-26. doi: 10.14740/jh1065. Epub 2023 Feb 25.
2
Successful combination chemotherapy involving clofarabine, cyclophosphamide, and etoposide for pediatric relapsed acute myeloid leukemia: A case report.成功应用氯法拉滨、环磷酰胺和依托泊苷联合化疗治疗儿童复发性急性髓系白血病：1例报告
SAGE Open Med Case Rep. 2021 May 13;9:2050313X211015511. doi: 10.1177/2050313X211015511. eCollection 2021.
3
Phase 1 study of bendamustine in combination with clofarabine, etoposide, and dexamethasone in pediatric patients with relapsed or refractory hematologic malignancies.儿童复发或难治性血液系统恶性肿瘤患者中苯达莫司汀联合克拉屈滨、依托泊苷和地塞米松的 1 期研究。
Cancer. 2021 Jun 15;127(12):2074-2082. doi: 10.1002/cncr.33465. Epub 2021 Feb 17.
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Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy.用于儿科癌症免疫治疗的基于细胞和抗体的方法。
J Immunol Res. 2015;2015:675269. doi: 10.1155/2015/675269. Epub 2015 Oct 26.
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Natural killer cell therapy in children with relapsed leukemia.复发白血病患儿的自然杀伤细胞疗法
Pediatr Blood Cancer. 2015 Aug;62(8):1468-72. doi: 10.1002/pbc.25555. Epub 2015 Apr 30.
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Overview of therapy and strategies for optimizing outcomes in de novo pediatric acute myeloid leukemia.初诊儿童急性髓系白血病的治疗概述及优化治疗效果的策略
Paediatr Drugs. 2014 Jun;16(3):213-27. doi: 10.1007/s40272-014-0067-3.
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Relapsed and refractory pediatric acute myeloid leukemia: current and emerging treatments.复发难治性儿童急性髓系白血病：现有及新出现的治疗方法。
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Exp Hematol Oncol. 2012 Dec 10;1(1):39. doi: 10.1186/2162-3619-1-39.
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Leukemia. 2013 Mar;27(3):569-77. doi: 10.1038/leu.2012.247. Epub 2012 Aug 28.

本文引用的文献

1
Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia.英国在使用克拉屈滨治疗复发/难治性儿童急性淋巴细胞白血病方面的早期经验。
Br J Haematol. 2011 Aug;154(4):482-5. doi: 10.1111/j.1365-2141.2011.08752.x. Epub 2011 Jun 21.
2
Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia.用克拉屈滨、环磷酰胺和依托泊苷进行单疗程再诱导治疗，用于治疗耐药/多重复发的急性淋巴细胞白血病患儿。
Br J Haematol. 2009 Nov;147(3):371-8. doi: 10.1111/j.1365-2141.2009.07882.x. Epub 2009 Aug 29.
3
A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia.一项关于克拉屈滨、依托泊苷和环磷酰胺联合治疗难治性或复发性急性白血病患儿的多中心 I 期研究。
Leukemia. 2009 Dec;23(12):2259-64. doi: 10.1038/leu.2009.185. Epub 2009 Sep 10.
4
Prognostic value of minimal residual disease quantification before allogeneic stem-cell transplantation in relapsed childhood acute lymphoblastic leukemia: the ALL-REZ BFM Study Group.异基因干细胞移植前微小残留病定量在儿童复发性急性淋巴细胞白血病中的预后价值：ALL-REZ BFM研究组
J Clin Oncol. 2009 Jan 20;27(3):377-84. doi: 10.1200/JCO.2008.17.6065. Epub 2008 Dec 8.
5
Prophylactic antibiotics reduce morbidity due to septicemia during intensive treatment for pediatric acute myeloid leukemia.预防性抗生素可降低小儿急性髓系白血病强化治疗期间败血症所致的发病率。
Cancer. 2008 Jul 15;113(2):376-82. doi: 10.1002/cncr.23563.
6
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.氯法拉滨联合阿糖胞苷（ara-C）治疗复发和难治性急性白血病的1-2期研究结果。
Blood. 2005 Feb 1;105(3):940-7. doi: 10.1182/blood-2004-05-1933. Epub 2004 Oct 14.
7
DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine.4-氢过氧环磷酰胺在慢性淋巴细胞白血病淋巴细胞中引发的DNA修复受到氟达拉滨和氯法拉滨的抑制。
Clin Cancer Res. 2001 Nov;7(11):3580-9.
8
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia.儿童急性淋巴细胞白血病微小残留病的临床重要性
Blood. 2000 Oct 15;96(8):2691-6.