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瑞士 2 型糖尿病的患病率、知晓率和治疗情况:CoLaus 研究。

Prevalence, awareness and treatment of type 2 diabetes mellitus in Switzerland: the CoLaus study.

机构信息

Department of Medicine Institute of Social and Preventive Medicine, Faculty of Biology and Medicine and Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

出版信息

Diabet Med. 2012 Feb;29(2):190-7. doi: 10.1111/j.1464-5491.2011.03422.x.

DOI:10.1111/j.1464-5491.2011.03422.x
PMID:21883431
Abstract

AIMS

To assess the prevalence, awareness and treatment levels of Type 2 diabetes in a Swiss city.

METHODS

Population-based cross-sectional study of 6181 subjects (3246 women) aged 35-75 years living in Lausanne, Switzerland. Type 2 diabetes was defined as fasting plasma glucose ≥ 7 mmol/l and/or oral hypoglycaemic treatment and/or insulin.

RESULTS

Total prevalence of Type 2 diabetes was 6.3% (95% confidence interval: 5.7-7.0%), higher in men (9.1%) than in women (3.8%, P < 0.001) and increased with age. Two-thirds (65.3%; 60.4-70.0%) of participants with Type 2 diabetes were aware of their status and among those aware 86.0% (81.5-90.3%) were treated. Treatment was more frequent in men (91.3%) than in women (75.9%, P < 0.001). Two-thirds of those treated for Type 2 diabetes were on monotherapy. Biguanides were prescribed in 65.0% of Type 2 diabetes patients and represented 48% of all antidiabetic drugs. Multivariable analysis showed male gender, increasing age, waist or BMI to be positively associated with prevalence of Type 2 diabetes, while leisure-time physical activity and alcohol consumption were negatively associated. Among participants presenting with Type 2 diabetes, increasing age was positively associated with awareness of Type 2 diabetes. Among subjects diagnosed with Type 2 diabetes, male gender and increasing age were positively associated with treatment.

CONCLUSION

Prevalence of Type 2 diabetes in Switzerland is estimated to be between 5.7% and 7.0%. Two-thirds of patients with Type 2 diabetes are aware of their status, and over three quarters of those aware are treated.

摘要

目的

评估瑞士洛桑市 2 型糖尿病的患病率、知晓率和治疗水平。

方法

对瑞士洛桑市 6181 名(3246 名女性)年龄在 35-75 岁的居民进行基于人群的横断面研究。2 型糖尿病的定义为空腹血糖≥7mmol/L 和/或口服降糖药治疗和/或胰岛素治疗。

结果

2 型糖尿病总患病率为 6.3%(95%置信区间:5.7%-7.0%),男性(9.1%)高于女性(3.8%,P<0.001),且随年龄增长而增加。65.3%(60.4%-70.0%)的 2 型糖尿病患者知晓其病情,其中 86.0%(81.5%-90.3%)接受治疗。男性(91.3%)的治疗率高于女性(75.9%,P<0.001)。接受 2 型糖尿病治疗的患者中,有三分之二接受单药治疗。二甲双胍在 2 型糖尿病患者中的使用率为 65.0%,占所有抗糖尿病药物的 48%。多变量分析显示,男性、年龄增长、腰围或 BMI 与 2 型糖尿病患病率呈正相关,而休闲时间体力活动和饮酒与 2 型糖尿病患病率呈负相关。在患有 2 型糖尿病的患者中,年龄增长与 2 型糖尿病的知晓率呈正相关。在被诊断为 2 型糖尿病的患者中,男性和年龄增长与治疗呈正相关。

结论

瑞士 2 型糖尿病的患病率估计在 5.7%-7.0%之间。三分之二的 2 型糖尿病患者知晓其病情,其中超过四分之三的患者得到治疗。

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