University of Chicago, Chicago, Illinois 60637, USA.
J Am Soc Echocardiogr. 2011 Dec;24(12):1319-24. doi: 10.1016/j.echo.2011.07.013. Epub 2011 Aug 31.
The rapid detection of left ventricular systolic dysfunction (LVSD) is an important step in the clinical management of patients admitted with acute decompensated heart failure, because it allows the initiation of treatment specific to LVSD and avoidance of contraindicated therapies. The aim of this study was to determine whether internal medicine residents with limited ultrasound training could use hand-carried ultrasound (HCU) to identify LVSD.
Fifty patients admitted with acute decompensated heart failure were imaged from the parasternal window at the bedside with an HCU device by residents blinded to all clinical data, who had undergone limited cardiac ultrasound training (20 practice studies). Ejection fraction (EF) on HCU was graded as >40% or <40%. HCU EF and a number of physical exam findings and electrocardiographic and laboratory variables were compared for their ability to predict to formal echocardiographic left ventricular EF.
The average formal EF was 32 ± 16% (range, 7%-70%), with 66% of patients having EFs < 40%. The residents' ability to detect an EF < 40% with HCU was excellent (sensitivity, 94%; specificity, 94%; negative predictive value, 88%; positive predictive value, 97%). Binary logistic regression demonstrated that HCU EF was the most powerful predictor of EF < 40%, with minimal additional value from clinical, exam, lab, and electrocardiographic variables. The time interval between clinical assessment and availability of formal echocardiographic results was 22 ± 17 hours.
Residents with limited training in cardiac ultrasound were able to identify LVSD in patients with acute decompensated heart failure with superior accuracy compared with clinical, physical exam, lab, and electrocardiographic findings and an average of 22 hours before the results of formal echocardiography were available.
快速检测左心室收缩功能障碍(LVSD)是急性失代偿性心力衰竭患者临床管理的重要步骤,因为它可以启动针对 LVSD 的治疗,并避免禁忌治疗。本研究旨在确定接受有限超声培训的内科住院医师是否可以使用手持式超声(HCU)来识别 LVSD。
对 50 名因急性失代偿性心力衰竭入院的患者进行了心前区窗旁床旁 HCU 成像,由对所有临床数据均不知情的接受过有限心脏超声培训(20 次实践研究)的住院医师进行。HCU 的射血分数(EF)分级为>40%或<40%。HCU EF 与多项体格检查发现以及心电图和实验室变量进行比较,以评估其预测正式超声心动图左心室 EF 的能力。
平均正式 EF 为 32 ± 16%(范围,7%-70%),有 66%的患者 EF<40%。住院医师使用 HCU 检测 EF<40%的能力非常出色(敏感性为 94%,特异性为 94%,阴性预测值为 88%,阳性预测值为 97%)。二元逻辑回归表明,HCU EF 是 EF<40%的最强预测因子,而临床、检查、实验室和心电图变量的额外价值很小。临床评估与正式超声心动图结果可用之间的时间间隔为 22 ± 17 小时。
接受过有限心脏超声培训的住院医师能够以比临床、体格检查、实验室和心电图发现更准确的方式识别急性失代偿性心力衰竭患者的 LVSD,并且在获得正式超声心动图结果之前平均提前 22 小时。