Optometry and Vision Research, Weinheim, Germany.
Cont Lens Anterior Eye. 2012 Apr;35(2):77-80. doi: 10.1016/j.clae.2011.08.003. Epub 2011 Aug 31.
Meibography is reported to be important in Meibomian Gland Dysfunction (MGD) evaluation. Our purpose was to investigate the usefulness of a standard infra-red video security camera in meibography.
Meibographs were taken of the right lower lid of 17 subjects (female 10; age = 44.3 years ±13.3 SD), randomly selected from the patient pool of Horst Riede GmbH, Weinheim, Germany. Meibomian glands (MG) were photographed by an near adapted infra-red video security camera and extend of MG loss (MGL) was measured by digital image analyzes. Lipid-layer and non-invasive break-up time (NIBUT) was measured by tearscope, dry eye symptoms were evaluated by the Ocular Surface Disease Index (OSDI). Correlations between MGL scores and ocular signs, tearfilm and symptoms were analyzed by Pearsons, differences between gender by U-test. The ability of MGL to predict dry eye symptoms was evaluated by area under the receiver operative characteristic curve (AUC).
MGL scores were significantly correlated to lipid-layer pattern (r = -0.68, p = 0.001) NIBUT (-0.46, 0.032) OSDI (0.89, 0.001) and age (0.61, 0.005). MGL was significantly larger in female (p = 0.001). AUC of MGL was 95.8% (p = 0.001; sensitivity = 88.9%; specificity = 87.5%; threshold = 32.3%).
MGL is a predictive test of dry eye symptoms. The analyzed significant correlation between MGL and tearfilm and dry eye symptoms indicates the usefulness of the non-contact IR meibograph (PNCM).
睑板腺功能障碍（MGD）的评估中，睑板腺照相术很重要。本研究旨在探讨标准近红外视频安防摄像机在睑板腺照相术中的应用价值。
从德国魏恩海姆霍斯特里德有限公司的患者群体中随机选择 17 名受试者（女性 10 名；年龄=44.3 岁±13.3 岁标准差）的右下眼睑进行睑板腺照相。使用近红外视频安防摄像机对睑板腺进行拍照，并通过数字图像分析测量睑板腺缺失程度（MGL）。使用泪膜镜测量脂质层和非侵入性泪膜破裂时间（NIBUT），使用眼表面疾病指数（OSDI）评估干眼症状。通过 Pearson 分析 MGL 评分与眼部体征、泪膜和症状之间的相关性，通过 U 检验分析性别之间的差异。通过受试者工作特征曲线（ROC）下面积（AUC）评估 MGL 预测干眼症状的能力。
MGL 评分与脂质层模式（r=-0.68，p=0.001）、NIBUT（-0.46，0.032）、OSDI（0.89，0.001）和年龄（0.61，0.005）显著相关。女性的 MGL 明显更大（p=0.001）。MGL 的 AUC 为 95.8%（p=0.001；敏感性=88.9%；特异性=87.5%；阈值=32.3%）。
MGL 是干眼症状的预测性测试。MGL 与泪膜和干眼症状之间的显著相关性表明非接触式近红外睑板腺照相术（PNCM）的有用性。
