Tomasini Dawn N, Segu Bhagya
VA Hudson Valley Healthcare System, Optometry Service, Castle Point, NY 12511, USA.
Optometry. 2007 Aug;78(8):402-8. doi: 10.1016/j.optm.2006.12.017.
Central retinal vein occlusion (CRVO) is a common cause of visual impairment and can occur at any age. Nonetheless, 90% of patients with CRVO are older than 50 years, and only 10% of CRVO patients are younger than 40 years. Systemic vascular diseases, such as hypertension and diabetes, are common risk factors for the development of CRVO. However, when a patient less than 50 years of age has bilateral and simultaneous central retinal vein occlusions, a hyperviscosity syndrome or inflammatory condition is also suspected.
This article presents the case of a 40-year-old man with bilateral ischemic CRVO and the differential diagnoses considered, including systemic lupus erythematosus (SLE), antiphospholipid antibody syndrome (APAS), dysproteinemias, and hyperhomocysteinemia.
When a CRVO is observed in a young patient, more obscure underlying etiologies must be explored. As primary care providers, optometrists need to consider common (and atypical) vascular risk factors for vein occlusion to prevent further ocular morbidity and systemic complications.
视网膜中央静脉阻塞(CRVO)是视力损害的常见原因,可发生于任何年龄。尽管如此,90%的CRVO患者年龄超过50岁,只有10%的CRVO患者年龄小于40岁。系统性血管疾病,如高血压和糖尿病,是CRVO发生的常见危险因素。然而,当一名年龄小于50岁的患者出现双侧同时性视网膜中央静脉阻塞时,也会怀疑存在高黏滞综合征或炎症性疾病。
本文介绍了一名40岁双侧缺血性CRVO男性患者的病例以及所考虑的鉴别诊断,包括系统性红斑狼疮(SLE)、抗磷脂抗体综合征(APAS)、蛋白异常血症和高同型半胱氨酸血症。
当在年轻患者中观察到CRVO时,必须探究更隐匿的潜在病因。作为初级保健提供者,验光师需要考虑静脉阻塞常见(和非典型)的血管危险因素,以预防进一步的眼部疾病和全身并发症。