Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Phytochemistry. 2011 Dec;72(17):2212-8. doi: 10.1016/j.phytochem.2011.08.001. Epub 2011 Aug 31.
A total of 20 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia angustiloba, of which two are hitherto unknown. One is an alkaloid of the angustilobine type (angustilobine C), while the other is a bisindole alkaloid angustiphylline, derived from the union of uleine and secovallesamine moieties. The structures of these alkaloids were established using NMR and MS analysis. Angustilobine C showed moderate cytotoxicity towards KB cells.
从垂茉莉的叶和茎皮提取物中共分离得到 20 种生物碱，其中两种为新生物碱。一种为阿枯米灵型生物碱（阿枯米灵 C），另一种为双吲哚生物碱垂茉莉菲灵，由猪毛菜碱和 secovallesamine 部分结合而成。这些生物碱的结构通过 NMR 和 MS 分析确定。阿枯米灵 C 对 KB 细胞显示出中等的细胞毒性。
