Macabeo Allan Patrick G, Krohn Karsten, Gehle Dietmar, Read Roger W, Brophy Joseph J, Cordell Geoffrey A, Franzblau Scott G, Aguinaldo Alicia M
Phytochemistry Laboratory, Research Center for the Natural Sciences, Thomas Aquinas Research Complex, University of Santo Tomas, Espana St., Manila 1008, Philippines.
Phytochemistry. 2005 May;66(10):1158-62. doi: 10.1016/j.phytochem.2005.02.018.
The first seco-uleine alkaloids, manilamine (1) (18-hydroxy-19,20-dehydro-7,21-seco-uleine) and N4-methyl angustilobine B (2), were isolated from the (pH 5) alkaloid extract of Philippine Alstonia scholaris leaves together with the known indole alkaloids 19,20-(E)-vallesamine (3), angustilobine B N4-oxide (4), 20(S)-tubotaiwine (5), and 6,7-seco-angustilobine B (6). The structure of the alkaloids was established from MS and NMR experiments.
从菲律宾鸡骨常山叶子的（pH 5）生物碱提取物中分离出了首批裂乌灵碱生物碱，马尼拉胺（1）（18-羟基-19,20-脱氢-7,21-裂乌灵碱）和N4-甲基狭叶罗平碱B（2），以及已知的吲哚生物碱19,20-(E)-瓦勒萨明（3）、狭叶罗平碱B N4-氧化物（4）、20(S)-图波台文（5）和6,7-裂狭叶罗平碱B（6）。通过质谱和核磁共振实验确定了这些生物碱的结构。
