BRAI²N & Department of Neurosurgery, University Hospital Antwerp, Belgium.
Auton Neurosci. 2011 Dec 7;165(2):191-4. doi: 10.1016/j.autneu.2011.06.007. Epub 2011 Sep 1.
Tinnitus affects 15% of the population. Of these 1-2% are severely disabled by it. The role of the autonomic system in tinnitus is hardly being investigated. The aim of this study is to investigate the relationship between tinnitus distress and lateralization of the anterior insula, known to be involved in interoceptive awareness and (para)sympathetic changes. For this, Tinnitus Questionnaire scores are correlated to Heart Rate Variability markers, and related to neural activity in left and right anterior insula. Our results show that tinnitus distress is related to sympathetic activation, in part mediated via the right anterior insula.
耳鸣影响了 15%的人群。其中 1-2%的人深受其扰。自主神经系统在耳鸣中的作用几乎没有被研究过。本研究旨在探讨已知与内脏感知和（副）交感变化有关的前岛叶偏侧化与耳鸣困扰之间的关系。为此，将耳鸣问卷评分与心率变异性标志物相关联，并与左右前岛叶的神经活动相关联。我们的结果表明，耳鸣困扰与交感神经激活有关，部分通过右侧前岛叶介导。
