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根据亚群效应解释谱系标记。

Interpreting lineage markers in view of subpopulation effects.

机构信息

ESR, Private Bag 92021, Auckland, New Zealand.

出版信息

Forensic Sci Int Genet. 2012 May;6(3):393-7. doi: 10.1016/j.fsigen.2011.04.020. Epub 2011 Sep 1.

Abstract

The interpretation of lineage markers is usually carried out as a count in a database. The count is a factual statement and does not take into account subpopulation effects that may be acting on the data. Subpopulation effects are usually taken into consideration for autosomal DNA genotype interpretation by the incorporation of a correction, θ. The question has arisen as to whether lineage markers should also have such a correction. This paper discusses if and how subpopulation effects could be considered.

摘要

谱系标记的解释通常在数据库中进行计数。计数是一个事实陈述,不考虑可能对数据产生影响的亚群效应。通常通过引入校正因子θ来考虑常染色体 DNA 基因型解释中的亚群效应。现在出现了一个问题,即谱系标记是否也应该进行这种校正。本文讨论了是否以及如何考虑亚群效应。

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