Bacterial Stress Response Group, Microbiology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland.
Appl Environ Microbiol. 2011 Nov;77(21):7841-5. doi: 10.1128/AEM.05732-11. Epub 2011 Sep 2.
The osmotic activation of sigma B (σ(B)) in Listeria monocytogenes was studied by monitoring expression of four known σ(B)-dependent genes, opuCA, lmo2230, lmo2085, and sigB. Activation was found to be rapid, transient, and proportional to the magnitude of the osmotic stress applied, features that underpin the adaptability of this pathogen.
我们通过监测四种已知依赖于σ(B)的基因(opuCA、lmo2230、lmo2085 和 sigB)的表达来研究李斯特菌中σB 的渗透激活。结果发现,这种激活是快速、短暂的,并且与施加的渗透压大小成正比,这些特征是这种病原体适应性的基础。