Matereke Lavious Tapiwa, Okoh Anthony Ifeanyi
SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice 5700, South Africa.
Applied and Environmental Microbiology Research Group, Department of Biochemistry and Microbiology, University of Fort Hare, Alice 5700, South Africa.
Pathogens. 2020 Jun 30;9(7):528. doi: 10.3390/pathogens9070528.
is a ubiquitous opportunistic pathogen responsible for the well-known listeriosis disease. This bacterium has become a common contaminant of food, threatening the food processing industry. Once consumed, the pathogen is capable of traversing epithelial barriers, cellular invasion, and intracellular replication through the modulation of virulence factors such as internalins and haemolysins. Mobile genetic elements (plasmids and transposons) and other sophisticated mechanisms are thought to contribute to the increasing antimicrobial resistance of . The environmental persistence of the pathogen is aided by its ability to withstand environmental stresses such as acidity, cold stress, osmotic stress, and oxidative stress. This review seeks to give an insight into biology, with emphasis on its virulence factors, antimicrobial resistance, and adaptations to environmental stresses.
是一种无处不在的机会致病菌，可引发著名的李斯特菌病。这种细菌已成为食品中的常见污染物，威胁着食品加工业。一旦被摄入，该病原体能够通过调节诸如内化素和溶血素等毒力因子来穿越上皮屏障、进行细胞侵袭和细胞内复制。移动遗传元件（质粒和转座子）及其他复杂机制被认为导致了该菌日益增强的抗菌耐药性。该病原体在环境中的持久性得益于其耐受诸如酸性、冷应激、渗透应激和氧化应激等环境压力的能力。本综述旨在深入了解该菌的生物学特性，重点关注其毒力因子、抗菌耐药性以及对环境压力的适应性。
