Interfakultäres Institut für Mikrobiologie und Infektionsmedizin Tübingen IMIT, Mikrobiologie/Biotechnologie, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 28, 72076 Tübingen, Germany.
J Bacteriol. 2011 Nov;193(21):6080-5. doi: 10.1128/JB.05782-11. Epub 2011 Sep 2.
Streptomyces coelicolor contains two gene clusters putatively involved in wall teichoic acid biosynthesis. Inactivation of the tagF homologue SCO2997 or SCO2584, a component of the Streptomyces spore wall synthesizing complex, affected sporulation. The mutant phenotypes resembled those of mre mutants, suggesting a function of wall teichoic acids in the differentiation of Streptomyces.
链霉菌色杆菌含有两个可能参与细胞壁磷壁酸生物合成的基因簇。tagF 同源物 SCO2997 或 SCO2584 的失活,这是链霉菌孢子壁合成复合物的一个组成部分,影响了孢子形成。突变表型类似于 mre 突变体,表明细胞壁磷壁酸在链霉菌分化中的作用。