Department of chemistry, Huzhou Teachers College, Huzhou 313000, China.
Int J Biol Macromol. 2011 Dec 1;49(5):1012-5. doi: 10.1016/j.ijbiomac.2011.08.023. Epub 2011 Aug 27.
Sulfated polysaccharide extracted from blue algae Enteromorpha linza is proved to possess excellent antioxidant activities. Two derivatives by means of oversulfated and acetylated coupling were synthesized and investigated their antioxidant activities including scavenging effect of superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl radicals. And then the relationship between antioxidant activity and chemical characteristics was characterized. The results of chemical analysis and FT-IR showed that the modification of polysaccharide was successful. In addition, it was found that certain derivatives exhibited stronger antioxidant activity than raw material. They could serve as free-radical inhibitors or scavengers, acting possibly as primary antioxidants.
从蓝藻石莼中提取的硫酸多糖被证明具有优异的抗氧化活性。通过过度硫酸化和乙酰化偶联两种方法合成了两种衍生物，并研究了它们的抗氧化活性，包括对超氧自由基、羟基自由基和 1,1-二苯基-2-苦基肼自由基的清除作用。然后，对抗氧化活性与化学特性之间的关系进行了表征。化学分析和 FT-IR 的结果表明多糖的修饰是成功的。此外，还发现某些衍生物的抗氧化活性比原料更强。它们可以作为自由基抑制剂或清除剂，可能作为主要的抗氧化剂。
