Zhang Zhongshan, Zhang Quanbin, Wang Jing, Zhang Hong, Niu Xizhen, Li Pengcheng
Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Int J Biol Macromol. 2009 Jul 1;45(1):22-6. doi: 10.1016/j.ijbiomac.2009.03.009. Epub 2009 Apr 2.
Porphyran extracted from Porphyra haitanensis is a sulfated polysaccharide, which possesses excellent antioxidant activities. In this study, we prepared one low-molecular-weight porphyran and its sulfated, acetylated, phosphorylated and benzoylated derivatives. Their antioxidant activities were investigated including scavenging effect of superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl radicals. The results of chemical analysis and FT-IR spectrums showed the modification was successful. And in addition, we found that certain derivative exhibited stronger antioxidant activity than low-molecular-weight porphyran. The benzoylated derivative showed the most excellent antioxidant activity in three assays, so this derivative needs to be attended to.
从坛紫菜中提取的紫菜多糖是一种硫酸化多糖，具有优异的抗氧化活性。在本研究中，我们制备了一种低分子量紫菜多糖及其硫酸化、乙酰化、磷酸化和苯甲酰化衍生物。研究了它们的抗氧化活性，包括对超氧阴离子、羟基和1,1-二苯基-2-苦基肼自由基的清除作用。化学分析和傅里叶变换红外光谱结果表明修饰成功。此外，我们发现某些衍生物表现出比低分子量紫菜多糖更强的抗氧化活性。苯甲酰化衍生物在三种测定中表现出最优异的抗氧化活性，因此该衍生物值得关注。
