Department of Preventive Medicine,Dongguk University College of Medicine,South Korea.
Division of Vaccine Research,Korea Centers for Disease Control and Prevention,South Korea.
Epidemiol Infect. 2015 Feb;143(3):515-21. doi: 10.1017/S0950268814001332. Epub 2014 May 27.
In February 2012, an outbreak of gastroenteritis was reported in school A; a successive outbreak was reported at school B. A retrospective cohort study conducted in school A showed that seasoned green seaweed with radishes (relative risk 7·9, 95% confidence interval 1·1-56·2) was significantly associated with illness. Similarly, a case-control study of students at school B showed that cases were 5·1 (95% confidence interval 1·1-24·8) times more likely to have eaten seasoned green seaweed with pears. Multiple norovirus genotypes were detected in samples from students in schools A and B. Norovirus GII.6 isolated from schools A and B were phylogenetically indistinguishable. Green seaweed was supplied by company X, and norovirus GII.4 was isolated from samples of green seaweed. Green seaweed was assumed to be linked to these outbreaks. To our knowledge, this is the first reported norovirus outbreak associated with green seaweed.
2012 年 2 月，A 校发生了一起肠胃炎暴发疫情；随后 B 校也暴发了疫情。在 A 校开展的一项回顾性队列研究显示，拌萝卜的海草（相对危险度 7.9，95%置信区间 1.1-56.2）与发病显著相关。同样，对 B 校学生的病例对照研究表明，病例组食用拌有梨的海草的可能性是对照组的 5.1 倍（95%置信区间 1.1-24.8）。从 A 校和 B 校学生的样本中检测到了多种诺如病毒基因型。从 A 校和 B 校分离到的诺如病毒 GII.6 在系统进化上无法区分。海草由 X 公司供应，从海草样本中分离到了诺如病毒 GII.4。海草被认为与这些暴发疫情有关。据我们所知，这是首次报告与海草有关的诺如病毒暴发疫情。
