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睡眠中的大脑作为一个复杂系统。

The sleeping brain as a complex system.

机构信息

Max Planck Institute for Mathematics in the Sciences, Inselstraße 22, 04103 Leipzig, Germany.

出版信息

Philos Trans A Math Phys Eng Sci. 2011 Oct 13;369(1952):3697-707. doi: 10.1098/rsta.2011.0199.

DOI:10.1098/rsta.2011.0199
PMID:21893523
Abstract

'Complexity science' is a rapidly developing research direction with applications in a multitude of fields that study complex systems consisting of a number of nonlinear elements with interesting dynamics and mutual interactions. This Theme Issue 'The complexity of sleep' aims at fostering the application of complexity science to sleep research, because the brain in its different sleep stages adopts different global states that express distinct activity patterns in large and complex networks of neural circuits. This introduction discusses the contributions collected in the present Theme Issue. We highlight the potential and challenges of a complex systems approach to develop an understanding of the brain in general and the sleeping brain in particular. Basically, we focus on two topics: the complex networks approach to understand the changes in the functional connectivity of the brain during sleep, and the complex dynamics of sleep, including sleep regulation. We hope that this Theme Issue will stimulate and intensify the interdisciplinary communication to advance our understanding of the complex dynamics of the brain that underlies sleep and consciousness.

摘要

“复杂性科学”是一个快速发展的研究方向,其应用涉及多个领域,研究由多个具有有趣动力学和相互作用的非线性元素组成的复杂系统。本期特刊“睡眠的复杂性”旨在促进复杂性科学在睡眠研究中的应用,因为大脑在不同的睡眠阶段会采用不同的整体状态,在神经回路的大型和复杂网络中表现出不同的活动模式。本引言讨论了本期特刊中收录的论文。我们强调了采用复杂系统方法的潜力和挑战,以理解大脑的一般状态,特别是睡眠中的大脑。基本上,我们专注于两个主题:理解睡眠期间大脑功能连接变化的复杂网络方法,以及包括睡眠调节在内的睡眠复杂动力学。我们希望本期特刊将激发并加强跨学科交流,以增进我们对睡眠和意识的大脑复杂动力学的理解。

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1
The sleeping brain as a complex system.睡眠中的大脑作为一个复杂系统。
Philos Trans A Math Phys Eng Sci. 2011 Oct 13;369(1952):3697-707. doi: 10.1098/rsta.2011.0199.
2
Awaking and sleeping of a complex network.一个复杂网络的觉醒与睡眠
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Nonlinear dynamical analysis of EEG and MEG: review of an emerging field.脑电图和脑磁图的非线性动力学分析:一个新兴领域的综述
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[Dynamic paradigm in psychopathology: "chaos theory", from physics to psychiatry].[精神病理学中的动态范式:“混沌理论”,从物理学到精神病学]
Encephale. 2001 May-Jun;27(3):260-8.
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Characterizing dynamic functional connectivity across sleep stages from EEG.通过脑电图表征睡眠各阶段的动态功能连接性。
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Small-world network organization of functional connectivity of EEG slow-wave activity during sleep.睡眠期间脑电图慢波活动功能连接的小世界网络组织
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Introduction to Focus Issue: synchronization in complex networks.焦点问题介绍:复杂网络中的同步
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Philos Trans A Math Phys Eng Sci. 2011 Oct 13;369(1952):3708-29. doi: 10.1098/rsta.2011.0078.
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The multiple time scales of sleep dynamics as a challenge for modelling the sleeping brain.睡眠动力学的多时间尺度对睡眠大脑建模的挑战。
Philos Trans A Math Phys Eng Sci. 2011 Oct 13;369(1952):3884-901. doi: 10.1098/rsta.2011.0082.
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The cognitive neuroscience of sleep: neuronal systems, consciousness and learning.睡眠的认知神经科学:神经元系统、意识与学习
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