Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Philos Trans R Soc Lond B Biol Sci. 2011 Oct 12;366(1579):2733-42. doi: 10.1098/rstb.2011.0076.
Vaccines have made a major contribution to global health in recent decades but they could do much more. In November 2011, a Royal Society discussion meeting, 'New vaccines for global health', was held in London to discuss the past contribution of vaccines to global health and to consider what more could be expected in the future. Papers presented at the meeting reviewed recent successes in the deployment of vaccines against major infections of childhood and the challenges faced in developing vaccines against some of the world's remaining major infectious diseases such as human immunodeficiency virus (HIV), malaria and tuberculosis. The important contribution that development of more effective veterinary vaccines could make to global health was also addressed. Some of the social and financial challenges to the development and deployment of new vaccines were reviewed. The latter issues were also discussed at a subsequent satellite meeting, 'Accelerating vaccine development', held at the Kavli Royal Society International Centre. Delegates at this meeting considered challenges to the more rapid development and deployment of both human and veterinary vaccines and how these might be addressed. Papers based on presentations at the discussion meeting and a summary of the main conclusions of the satellite meeting are included in this issue of Philosophical Transactions of the Royal Society B.
几十年来，疫苗为全球健康做出了重大贡献，但它们还可以发挥更大的作用。2011 年 11 月，英国皇家学会在伦敦举行了一次题为“新疫苗应对全球健康挑战”的座谈会，讨论了疫苗过去对全球健康的贡献，并探讨了未来还能有哪些更多的期待。会议上提交的论文回顾了最近在部署针对儿童主要传染病的疫苗方面取得的成功，以及在开发针对世界上一些仍存在的主要传染病（如人类免疫缺陷病毒（HIV）、疟疾和结核病）的疫苗方面所面临的挑战。还讨论了开发更有效的兽医疫苗对全球健康可能产生的重要贡献。会议还审议了新疫苗的开发和应用所面临的一些社会和财政挑战。这些问题也在随后的一次卫星会议“加速疫苗开发”上进行了讨论，该会议在英国皇家学会国际中心举行。与会代表在会上讨论了人类和兽医疫苗更快开发和应用的挑战，以及如何应对这些挑战。本次座谈会的讨论文件和卫星会议的主要结论摘要收录在本期《英国皇家学会哲学汇刊 B 辑》中。
