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用于确定现代 CT 系统的有效皮肤和乳房剂量的实用剂量测定方法,包含部分照射和前瞻性心脏门控。

Practical dosimetry methods for the determination of effective skin and breast dose for a modern CT system, incorporating partial irradiation and prospective cardiac gating.

机构信息

Department of Clinical and Radiation Physics, Directorate of Healthcare Science and Technology, Plymouth Hospitals NHS Trust, Plymouth, UK.

出版信息

Br J Radiol. 2012 Mar;85(1011):237-48. doi: 10.1259/bjr/22285164. Epub 2011 Sep 6.

DOI:10.1259/bjr/22285164
PMID:21896660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3473996/
Abstract

OBJECTIVE

For CT coronary angiography (CTCA), a generic chest conversion factor returns a significant underestimate of effective dose. The aim of this manuscript is to communicate new dosimetry methods to calculate weighted CT dose index (CTDIw), effective dose, entrance surface dose (ESD) and organ dose to the breast for prospectively gated CTCA.

METHODS

CTDIw in 32 cm diameter Perspex phantom was measured using an adapted technique, accounting for the segmented scan characteristic. Gafchromic XRCT film (International Speciality Products, New Jersey, NJ) was used to measure the distribution and magnitude of ESD. Breast dose was measured using high sensitivity metal oxide semiconductor field-effect transistors and compared to the computer based imaging performance assessment of CT scanners (ImPACT) dosimetry calculations.

RESULTS

For a typical cardiac scan the mean ESD remained broadly constant (7-9 mGy) when averaged over the circumference of the Perspex phantom. Typical absorbed dose to the breast with prospectively gated protocols was within the range 2-15 mGy. The subsequent lifetime attributable risk (LAR) of cancer incidence to the breast was found at 0.01-0.06 for a 20-year-old female. This compares favourably to 100 mGy (LAR ~0.43) for a retrospectively gated CTCA.

CONCLUSIONS

Care must be taken when considering radiation dosimetry associated with prospectively gated scanning for CTCA and a method has been conveyed to account for this. Breast doses for prospectively gated CTCA are an order of magnitude lower than retrospectively gated scans. Optimisation of cardiac protocols is expected to show further dose reduction.

摘要

目的

对于 CT 冠状动脉造影(CTCA),通用胸部转换因子会导致有效剂量的显著低估。本手稿的目的是交流新的剂量测量方法,以计算前瞻性门控 CTCA 的加权 CT 剂量指数(CTDIw)、有效剂量、入射表面剂量(ESD)和乳房器官剂量。

方法

使用改良技术在 32cm 直径的 Perspex 体模中测量 CTDIw,该技术考虑到分段扫描的特点。使用 Gafchromic XRCT 胶片(新泽西州国际特种产品公司,新泽西州)测量 ESD 的分布和大小。使用高灵敏度金属氧化物半导体场效应晶体管测量乳房剂量,并与基于计算机的 CT 扫描仪成像性能评估(ImPACT)剂量计算进行比较。

结果

对于典型的心脏扫描,当在 Perspex 体模的圆周上平均时,平均 ESD 基本保持不变(7-9mGy)。前瞻性门控方案中典型的乳房吸收剂量在 2-15mGy 范围内。20 岁女性乳房的随后终生归因风险(LAR)为 0.01-0.06,这与回顾性门控 CTCA 的 100mGy(LAR~0.43)相比是有利的。

结论

在考虑与前瞻性门控扫描相关的 CTCA 辐射剂量时必须谨慎,并且已经传达了一种方法来对此进行说明。前瞻性门控 CTCA 的乳房剂量比回顾性门控扫描低一个数量级。预计优化心脏方案将进一步降低剂量。

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