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用于放射治疗治疗计划的锥形束CT成像所产生的器官和有效剂量估算。

Estimation of organ and effective doses resulting from cone beam CT imaging for radiotherapy treatment planning.

作者信息

Sawyer L J, Whittle S A, Matthews E S, Starritt H C, Jupp T P

机构信息

Medical Physics and Bioengineering Department, Royal United Hospital, Combe Park, Bath BA1 3NG, UK.

出版信息

Br J Radiol. 2009 Jul;82(979):577-84. doi: 10.1259/bjr/62467578. Epub 2009 Mar 2.

Abstract

In this study, organ doses were measured for various kilovoltage cone beam CT exposures on the Varian Acuity simulator and an alternative method of dose estimation was also assessed. Organ doses were measured by distributing thermoluminescent dosimeters (TLDs) throughout an anthropomorphic phantom, and effective doses were calculated using International Commission on Radiological Protection (ICRP) 60 and ICRP 103 tissue-weighting factors. The ImPACT CT patient dosimetry calculator was also used to estimate doses for comparison with the TLD results. Effective doses of 15.3 mSv (19.4 mSv), 14.3 mSv (9.7 mSv) and 2.8 mSv (3.2 mSv) were calculated from the TLD measurements and ICRP 60 (ICRP 103) weighting factors for breast, pelvis and head acquisitions, respectively. When a 10 cm pencil ionisation chamber was used to measure the CT dose index, the ImPACT calculator was found to provide an adequate estimation of dose when compared with the TLD results. However, the doses for half-fan exposures were found to be overestimated, with the extent of overestimation depending on the radiosensitive organs irradiated. The organ and effective doses reported provide information for justification and optimisation of cone beam CT procedures, and are compared with doses delivered by other imaging devices. The ImPACT calculator may be used to estimate doses from cone beam CT procedures, if the potential for overestimation is acknowledged.

摘要

在本研究中,在瓦里安锐视力模拟器上对各种千伏锥束CT曝光进行了器官剂量测量,并评估了一种替代剂量估算方法。通过在人体模型中分布热释光剂量计(TLD)来测量器官剂量,并使用国际放射防护委员会(ICRP)60和ICRP 103组织权重因子计算有效剂量。还使用ImPACT CT患者剂量计算工具来估算剂量,以便与TLD结果进行比较。根据TLD测量结果以及ICRP 60(ICRP 103)权重因子,分别计算出乳腺成像、骨盆成像和头部成像的有效剂量为15.3 mSv(19.4 mSv)、14.3 mSv(9.7 mSv)和2.8 mSv(3.2 mSv)。当使用10 cm铅笔电离室测量CT剂量指数时,发现与TLD结果相比,ImPACT计算工具能够充分估算剂量。然而,发现半扇形曝光的剂量被高估,高估程度取决于受照射的放射敏感器官。报告的器官剂量和有效剂量为锥束CT程序的正当性论证和优化提供了信息,并与其他成像设备的剂量进行了比较。如果认识到存在高估的可能性,ImPACT计算工具可用于估算锥束CT程序的剂量。

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